{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T09:01:15Z","timestamp":1770973275948,"version":"3.50.1"},"reference-count":18,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,3,19]]},"abstract":"<jats:p>A 63-year-old man with infective endocarditis (IE) was admitted to our hospital after experiencing acute heart failure. A two-dimensional transthoracic and transesophageal echocardiography revealed vegetation attached to both aortic and mitral valves, a very large mitral valve aneurysm, a severe mitral regurgitation jet issuing from a mitral valve perforation and severe aortic regurgitation. Three days after admission, both the aortic and mitral valves were replaced. The patient received antibiotic therapy for 6\u2005weeks postoperatively and recovered with no neurological complications. Although the patient was discharged without recurrence of IE, his transthoracic and transesophageal echocardiography showed periprosthetic mitral regurgitation, requiring him to receive close follow-up monitoring. This case report exemplifies the rather unusual, but important, complications of aortic valve IE, and suggests some suitable forms of intervention.<\/jats:p>","DOI":"10.1136\/bcr-2014-209092","type":"journal-article","created":{"date-parts":[[2015,4,15]],"date-time":"2015-04-15T14:01:22Z","timestamp":1429106482000},"page":"bcr2014209092","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Large mitral valve aneurysm with infective endocarditis"],"prefix":"10.1136","volume":"2015","author":[{"given":"Shoko","family":"Uematsu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyomi","family":"Ashihara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideyuki","family":"Tomioka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Takagi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,4,15]]},"reference":[{"key":"2025042705595531000_2015.apr15_1.bcr2014209092.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(83)80272-1"},{"key":"2025042705595531000_2015.apr15_1.bcr2014209092.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)00206-4"},{"key":"2025042705595531000_2015.apr15_1.bcr2014209092.3","first-page":"476","article-title":"Review: mitral valve aneurysms in infective endocarditis: mechanisms, clinical recognition, and treatment","volume":"18","author":"Silbiger","year":"2009","journal-title":"J Heart Valve Dis"},{"key":"2025042705595531000_2015.apr15_1.bcr2014209092.4","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp285"},{"key":"2025042705595531000_2015.apr15_1.bcr2014209092.5","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-014-0365-4"},{"key":"2025042705595531000_2015.apr15_1.bcr2014209092.6","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0022-5223(19)42488-4","article-title":"The importance of the \u201cjet lesion\u201d in bacterial endocarditis involving the left heart. Surgical considerations","volume":"59","author":"Gonzalez-Lavin","year":"1970","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2025042705595531000_2015.apr15_1.bcr2014209092.7","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5273(84)90010-X"},{"key":"2025042705595531000_2015.apr15_1.bcr2014209092.8","doi-asserted-by":"crossref","unstructured":"Edynak GM , Rawson AJ . Ruptured aneurysm of the mitral valve in a Marfan-like syndrome. Am J Cardiol 1963;11:674\u20137. doi:10.1016\/0002-9149(63)90088-2","DOI":"10.1016\/0002-9149(63)90088-2"},{"key":"2025042705595531000_2015.apr15_1.bcr2014209092.9","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(03)01602-3"},{"key":"2025042705595531000_2015.apr15_1.bcr2014209092.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2004.04.013"},{"key":"2025042705595531000_2015.apr15_1.bcr2014209092.11","doi-asserted-by":"publisher","DOI":"10.1111\/echo.12449"},{"key":"2025042705595531000_2015.apr15_1.bcr2014209092.12","doi-asserted-by":"publisher","DOI":"10.1111\/echo.12356"},{"key":"2025042705595531000_2015.apr15_1.bcr2014209092.13","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2005.08.023"},{"key":"2025042705595531000_2015.apr15_1.bcr2014209092.14","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(94)90143-0"},{"key":"2025042705595531000_2015.apr15_1.bcr2014209092.15","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2006.09.023"},{"key":"2025042705595531000_2015.apr15_1.bcr2014209092.16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.09.034"},{"key":"2025042705595531000_2015.apr15_1.bcr2014209092.17","doi-asserted-by":"publisher","DOI":"10.1186\/s13019-014-0148-y"},{"key":"2025042705595531000_2015.apr15_1.bcr2014209092.18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2007.06.028"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2014-209092","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T13:00:16Z","timestamp":1745758816000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2014-209092"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,15]]},"references-count":18,"alternative-id":["10.1136\/bcr-2014-209092"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2014-209092","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,15]]}}}