{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T17:42:07Z","timestamp":1769103727948,"version":"3.49.0"},"reference-count":11,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,2,14]]},"abstract":"<jats:p>Neonatal immune hyperthyroidism is a rare but potentially fatal condition. It occurs in 1\u20135% of infants born to women with Graves\u2019 disease (GD). In most of the cases it is due to maternal antibodies transferred from the mother into the fetal compartment, stimulating the fetal thyroid by binding thyrotropin (thyroid-stimulating hormone, TSH) receptor. We present a case of neonatal thyrotoxicosis due to maternal GD detected at 25\u2005days of age and discuss the potential pitfalls in the diagnosis.<\/jats:p>","DOI":"10.1136\/bcr-2014-209283","type":"journal-article","created":{"date-parts":[[2015,3,6]],"date-time":"2015-03-06T11:01:58Z","timestamp":1425639718000},"page":"bcr2014209283","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Neonatal thyrotoxicosis caused by maternal autoimmune hyperthyroidism"],"prefix":"10.1136","volume":"2015","author":[{"given":"Miguel Fragata","family":"Correia","sequence":"first","affiliation":[{"name":"Departamento de Pediatria M\u00e9dica, Hospital Dona Estef\u00e2nia, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Teresa","family":"Maria","sequence":"additional","affiliation":[{"name":"Departamento da Mulher e da Crian\u00e7a, HPP Hospital de Cascais Dr Jos\u00e9 de Almeida, Alcabideche, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Prado","sequence":"additional","affiliation":[{"name":"Departamento da Mulher e da Crian\u00e7a, HPP Hospital de Cascais Dr Jos\u00e9 de Almeida, Alcabideche, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catarina","family":"Limbert","sequence":"additional","affiliation":[{"name":"Unidade de Endocrinologia, Hospital Dona Estef\u00e2nia, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,3,6]]},"reference":[{"key":"2025082805264966000_2015.mar06_2.bcr2014209283.1","doi-asserted-by":"publisher","DOI":"10.1159\/000092454"},{"key":"2025082805264966000_2015.mar06_2.bcr2014209283.2","unstructured":"Gowen CW . Maternal diseases affecting the newborn. In: Marcdante KJ , Kliegman RM, eds . Nelson essentials of pediatrics. 7th edn. Philadelphia: Elsevier Saunders, 2015:204\u20137; Chapter 59."},{"key":"2025082805264966000_2015.mar06_2.bcr2014209283.3","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0025-7125(16)30475-8","article-title":"Thyroid disease and pregnancy","volume":"75","author":"Becks","year":"1991","journal-title":"Med Clin North Am"},{"key":"2025082805264966000_2015.mar06_2.bcr2014209283.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4266(04)95660-0"},{"key":"2025082805264966000_2015.mar06_2.bcr2014209283.5","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-24-7-660"},{"issue":"(Suppl 1)","key":"2025082805264966000_2015.mar06_2.bcr2014209283.6","doi-asserted-by":"crossref","first-page":"S50","DOI":"10.4103\/2230-8210.119505","article-title":"Fetal and neonatal thyrotoxicosis","volume":"17","author":"Batra","year":"2013","journal-title":"Indian J Endocrinol Metab"},{"key":"2025082805264966000_2015.mar06_2.bcr2014209283.7","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-27302012000800009"},{"key":"2025082805264966000_2015.mar06_2.bcr2014209283.8","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2011.0087"},{"key":"2025082805264966000_2015.mar06_2.bcr2014209283.9","doi-asserted-by":"publisher","DOI":"10.1136\/fn.87.3.F165"},{"key":"2025082805264966000_2015.mar06_2.bcr2014209283.10","unstructured":"Bollepalli S , Rose SR . Disorders of the thyroid gland. In: Gleason CA , Devaskar SU, eds . Avery's diseases of the newborn. 9th edn. Philadelphia: Elsevier Saunders, 2015:1312\u201319."},{"key":"2025082805264966000_2015.mar06_2.bcr2014209283.11","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-010-0337-1"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2014-209283","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:27:00Z","timestamp":1756384020000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2014-209283"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,6]]},"references-count":11,"alternative-id":["10.1136\/bcr-2014-209283"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2014-209283","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,6]]}}}