{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:10:02Z","timestamp":1756307402235,"version":"3.44.0"},"reference-count":9,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,5,13]]},"abstract":"<jats:p>Spontaneous intracranial hypotension (SIH) usually occurs in the setting of a spontaneous cerebral spinal fluid (CSF) leak. We report the first description of a case of SIH caused by a CSF leak which improved after a targeted epidural patch with n-butyl cyanoacrylate (n-BCA) at the right T1\u2013T2 level. An 81-year-old woman presented with an orthostatic headache for 6\u2005days. MRI of the brain with contrast demonstrated low lying cerebellar tonsils, an engorged transverse sinus flow void, bifrontal small subdural fluid collections, and diffuse dural enhancement. CT myelography showed extravasation of intrathecal contrast at the right T1\u2013T2 level. A targeted epidural patch was performed by injection of n-BCA through a catheter at the right T1\u2013T2 level. After treatment, the patient's symptoms immediately improved and she was without a headache at 1-year follow-up.<\/jats:p>","DOI":"10.1136\/bcr-2015-011778","type":"journal-article","created":{"date-parts":[[2015,6,2]],"date-time":"2015-06-02T11:53:39Z","timestamp":1433246019000},"page":"bcr2015011778","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Targeted epidural patch with n-butyl cyanoacrylate (n-BCA) through a single catheter access site for treatment of a cerebral spinal fluid leak causing spontaneous intracranial hypotension"],"prefix":"10.1136","volume":"2015","author":[{"given":"Sean","family":"Woolen","sequence":"first","affiliation":[{"name":"Department of Radiology, University of Michigan Health System, Ann Arbor, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph J","family":"Gemmete","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Michigan Health System, Ann Arbor, Michigan, USA"},{"name":"Department of Neurosurgery, University of Michigan, Ann Arbor, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aditya S","family":"Pandey","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Michigan Health System, Ann Arbor, Michigan, USA"},{"name":"Department of Neurosurgery, University of Michigan, Ann Arbor, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neeraj","family":"Chaudhary","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Michigan Health System, Ann Arbor, Michigan, USA"},{"name":"Department of Neurosurgery, University of Michigan, Ann Arbor, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,6,2]]},"reference":[{"key":"2025082707491136000_2015.jun02_1.bcr2015011778.1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-211-85578-2_31"},{"key":"2025082707491136000_2015.jun02_1.bcr2015011778.2","doi-asserted-by":"crossref","first-page":"e6","DOI":"10.3171\/foc.2000.9.1.6","article-title":"Cerebrospinal fluid volume depletion and its emerging clinical\/imaging syndromes","volume":"9","author":"Mokri","year":"2000","journal-title":"Neurosurg Focus"},{"key":"2025082707491136000_2015.jun02_1.bcr2015011778.3","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2000.00153.x"},{"key":"2025082707491136000_2015.jun02_1.bcr2015011778.4","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2004.100.6.1098"},{"key":"2025082707491136000_2015.jun02_1.bcr2015011778.5","first-page":"155","article-title":"Idiopathic intracranial hypertension: a prospective study of 50 patients","volume":"114","author":"Durcan","year":"1991","journal-title":"Brain"},{"key":"2025082707491136000_2015.jun02_1.bcr2015011778.6","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-004-0025-5"},{"key":"2025082707491136000_2015.jun02_1.bcr2015011778.7","doi-asserted-by":"publisher","DOI":"10.1111\/head.12149"},{"key":"2025082707491136000_2015.jun02_1.bcr2015011778.8","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1998.88.2.0243"},{"key":"2025082707491136000_2015.jun02_1.bcr2015011778.9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2008.01776.x"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2015-011778","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:49:19Z","timestamp":1756306159000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2015-011778"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,2]]},"references-count":9,"alternative-id":["10.1136\/bcr-2015-011778"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2015-011778","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2015,6,2]]}}}