{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T15:09:30Z","timestamp":1769267370360,"version":"3.49.0"},"reference-count":10,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,4,14]]},"abstract":"<jats:p>A late preterm presented with tachypnoea, jitteriness, irritability and low grade fever. Blood gas showed a compensated metabolic acidosis. His mother was taking the selective serotonin reuptake inhibitor (SSRI) fluoxetine, 60\u2005mg\/day, and he was exclusively breast-fed. The baby's serum level of fluoxetine on day 8 was within the adult therapeutic range and his symptoms were ascribed to fluoxetine toxicity. On changing to formula feeds, his symptoms resolved. SSRIs are commonly administered during pregnancy, but SSRI toxicity in infants is rarely reported. It is possible that this condition is under diagnosed or, alternatively, misdiagnosed as SSRI withdrawal in breast fed infants whose mothers are on SSRIs. There is limited research looking at serotonin excess in neonates, making case reports such as this important in our learning. Increased awareness may prompt more frequent measurements of blood levels in breast-fed infants whose mothers are on SSRIs.<\/jats:p>","DOI":"10.1136\/bcr-2015-209418","type":"journal-article","created":{"date-parts":[[2015,5,6]],"date-time":"2015-05-06T06:50:43Z","timestamp":1430895043000},"page":"bcr2015209418","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":15,"title":["Serotonin syndrome in a breast-fed neonate"],"prefix":"10.1136","volume":"2015","author":[{"given":"Rachel","family":"Morris","sequence":"first","affiliation":[{"name":"Neonatal Department, Abertawe Bro Morgannwg University Health Board, Swansea, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean","family":"Matthes","sequence":"additional","affiliation":[{"name":"Neonatal Department, Abertawe Bro Morgannwg University Health Board, Swansea, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,5,6]]},"reference":[{"key":"2025082706524477000_2015.may06_1.bcr2015209418.1","unstructured":"Scottish Intercollegiate Guidelines Network (SIGN). Management of perinatal mood disorders. Edinburgh: SIGN, 2012. (SIGN publication no. 127). [March 2012]"},{"key":"2025082706524477000_2015.may06_1.bcr2015209418.2","doi-asserted-by":"publisher","DOI":"10.1097\/GRF.0b013e3181b52bd6"},{"key":"2025082706524477000_2015.may06_1.bcr2015209418.3","unstructured":"Hale TW . Medication and mother's milk. 13th edn. Hale Publishing, 2008:15 and 398."},{"key":"2025082706524477000_2015.may06_1.bcr2015209418.4","first-page":"19","article-title":"Assessment and treatment of abstinence in the infant of the drug-dependent mother","volume":"12","author":"Finnegan","year":"1975","journal-title":"Int Clin Pharmacol Biopharm"},{"key":"2025082706524477000_2015.may06_1.bcr2015209418.5","doi-asserted-by":"publisher","DOI":"10.1080\/14767050802266899"},{"key":"2025082706524477000_2015.may06_1.bcr2015209418.6","doi-asserted-by":"publisher","DOI":"10.1177\/0269881105056554"},{"key":"2025082706524477000_2015.may06_1.bcr2015209418.7","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.60.7.720"},{"key":"2025082706524477000_2015.may06_1.bcr2015209418.8","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcg109"},{"key":"2025082706524477000_2015.may06_1.bcr2015209418.9","doi-asserted-by":"publisher","DOI":"10.1136\/fn.85.2.F145g"},{"key":"2025082706524477000_2015.may06_1.bcr2015209418.10","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g1626"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2015-209418","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T13:52:52Z","timestamp":1756302772000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2015-209418"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,6]]},"references-count":10,"alternative-id":["10.1136\/bcr-2015-209418"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2015-209418","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,6]]}}}