{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T21:19:19Z","timestamp":1781903959949,"version":"3.54.5"},"reference-count":7,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,3,25]]},"abstract":"<jats:p>We present the case of a 33-year-old woman in her first pregnancy. She presented with pruritus at 34\u2005weeks gestation. A diagnosis of intrahepatic cholestasis of pregnancy was made based on elevated bile acids and elevated liver transaminases. She re-presented 4\u2005days later, jaundiced with abdominal pain and nausea, and was hypertensive. Her bilirubin was now elevated and her creatinine had doubled. The differential diagnosis-included pre-eclampsia and Hemolysis Elevated Liver enzymes Low Platelet count (HELLP) syndrome, and delivery was expedited. Postnatally, the patient became coagulopathic, though not thrombocytopaenic; she had persistent hypoglycaemia, hyponatraemia, developed acute pancreatitis and had profound ascites and peripheral oedema. Management was supportive with multidisciplinary care and over a period of 3\u2005weeks she made a full clinical and biochemical recovery.<\/jats:p>","DOI":"10.1136\/bcr-2015-209649","type":"journal-article","created":{"date-parts":[[2015,4,15]],"date-time":"2015-04-15T10:01:22Z","timestamp":1429092082000},"page":"bcr2015209649","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":16,"title":["Acute fatty liver of pregnancy with hypoglycaemia, diabetes insipidus and pancreatitis, preceded by intrahepatic cholestasis of pregnancy"],"prefix":"10.1136","volume":"2015","author":[{"given":"Nicola","family":"English","sequence":"first","affiliation":[{"name":"Department of Obstetrics & Gynaecology, King Edwards Memorial Hospital, Subiaco, Western Australia, Australia"},{"name":"Department of Obstetrics & Gynaecology, Joondalup Health Campus, Joondalup, Western Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jegajeeva","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynaecology, Joondalup Health Campus, Joondalup, Western Australia, Australia"},{"name":"Faculty of Medicine, University of New South Wales, UNSW Sydney, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2015,4,15]]},"reference":[{"key":"2025082804074495000_2015.apr15_1.bcr2015209649.1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2008.148676"},{"key":"2025082804074495000_2015.apr15_1.bcr2015209649.2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0029077"},{"key":"2025082804074495000_2015.apr15_1.bcr2015209649.3","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1040563"},{"key":"2025082804074495000_2015.apr15_1.bcr2015209649.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61495-1"},{"key":"2025082804074495000_2015.apr15_1.bcr2015209649.5","doi-asserted-by":"publisher","DOI":"10.1136\/gut.51.6.876"},{"key":"2025082804074495000_2015.apr15_1.bcr2015209649.6","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1016\/0016-5085(91)90292-S","article-title":"Intrahepatic cholestasis of pregnancy and acute fatty liver of pregnancy. An unusual but favourable association","volume":"100","author":"Vanjak","year":"1991","journal-title":"Gastroenterology"},{"key":"2025082804074495000_2015.apr15_1.bcr2015209649.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2003.09.022"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2015-209649","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:07:53Z","timestamp":1756379273000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2015-209649"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,15]]},"references-count":7,"alternative-id":["10.1136\/bcr-2015-209649"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2015-209649","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,15]]}}}