{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T10:30:25Z","timestamp":1762252225554,"version":"3.40.4"},"reference-count":10,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,5,26]]},"abstract":"<jats:p>A 47-year-old woman presented with a history of vague abdominal pain for several years, which worsened over the past 2\u2005months, with pain more prominent in the right upper quadrant. She also had a history of peptic ulcer disease. The ultrasound scan of right upper quadrant revealed normal gallbladder and oesophagogastroduodenoscopy was unremarkable. A<jats:sup>99m<\/jats:sup>technetium labelled hepato iminodiacetic acid (HIDA) scan with cholecystokinin provocation demonstrated a decreased gallbladder ejection fraction (EF) of 32%. On this basis, the patient was diagnosed with biliary dyskinesia and underwent an elective laparoscopic cholecystectomy. Histopathological analysis revealed chronic cholecystitis with<jats:italic>Cystoisospora belli<\/jats:italic>identified in the gallbladder wall.<jats:italic>Cystoisospora<\/jats:italic>has been identified to cause an opportunistic acalculous cholecystitis among immunocompromised hosts, especially those with AIDS. This is the first case report of chronic cholecystitis due to<jats:italic>C. belli<\/jats:italic>in an immunocompetent patient.<\/jats:p>","DOI":"10.1136\/bcr-2015-209966","type":"journal-article","created":{"date-parts":[[2015,6,11]],"date-time":"2015-06-11T13:15:41Z","timestamp":1434028541000},"page":"bcr2015209966","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Chronic cholecystitis with<i>Cystoisospora belli<\/i>in an immunocompetent patient"],"prefix":"10.1136","volume":"2015","author":[{"given":"Hideo","family":"Takahashi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gavin A","family":"Falk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Cruise","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gareth","family":"Morris-Stiff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,6,11]]},"reference":[{"key":"2025042706314489000_2015.jun11_1.bcr2015209966.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198607103150203"},{"key":"2025042706314489000_2015.jun11_1.bcr2015209966.2","first-page":"71","article-title":"Intestinal parasitic infections in patients with malignancy","volume":"17","author":"Rudrapatna","year":"1997","journal-title":"J Diarrhoeal Dis Res"},{"key":"2025042706314489000_2015.jun11_1.bcr2015209966.3","doi-asserted-by":"publisher","DOI":"10.4103\/0000-0205.72112"},{"key":"2025042706314489000_2015.jun11_1.bcr2015209966.4","doi-asserted-by":"publisher","DOI":"10.4103\/0974-777X.122012"},{"key":"2025042706314489000_2015.jun11_1.bcr2015209966.5","first-page":"1","article-title":"Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America","volume":"58","author":"Kaplan","year":"2009","journal-title":"MMWR Recomm Rep"},{"key":"2025042706314489000_2015.jun11_1.bcr2015209966.6","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-124-4-199602150-00008"},{"key":"2025042706314489000_2015.jun11_1.bcr2015209966.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2009.01.020"},{"key":"2025042706314489000_2015.jun11_1.bcr2015209966.8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1293.2007.00530.x"},{"key":"2025042706314489000_2015.jun11_1.bcr2015209966.9","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/21.4.852"},{"key":"2025042706314489000_2015.jun11_1.bcr2015209966.10","doi-asserted-by":"crossref","first-page":"94","DOI":"10.4269\/ajtmh.2001.65.94","article-title":"Nitazoxanide treatment failure in chronic isosporiasis","volume":"65","author":"Bialek","year":"2001","journal-title":"Am J Trop Med Hyg"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2015-209966","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T13:31:51Z","timestamp":1745760711000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2015-209966"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,11]]},"references-count":10,"alternative-id":["10.1136\/bcr-2015-209966"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2015-209966","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2015,6,11]]}}}