{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T09:20:06Z","timestamp":1774084806646,"version":"3.50.1"},"reference-count":13,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,7,15]]},"abstract":"<jats:p>Chikungunya fever is a vector borne virus that typically causes a self-limiting systemic illness with fever, skin rash and joint aches 2\u2005weeks after infection. We present the case of a 69-year-old woman presenting with an acute unilateral optic neuropathy as a delayed complication of Chikungunya virus (CHIKV) infection contracted during a recent trip to the West Indies. She presented to our ophthalmology department with acute painless visual field loss in the right eye and a recent flu-like illness. She was found to have a right relative afferent pupillary defect (RAPD) with unilateral optic disc swelling. Serology confirmed recent CHIKV infection. Treatment with intravenous methylprednisolone was delayed while awaiting MRI scans and serology results. At 5-month follow-up, there was a persistent right RAPD and marked optic atrophy with a corresponding inferior scotoma in the visual field.<\/jats:p>","DOI":"10.1136\/bcr-2015-210081","type":"journal-article","created":{"date-parts":[[2015,7,28]],"date-time":"2015-07-28T08:11:46Z","timestamp":1438071106000},"page":"bcr2015210081","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Chikungunya fever presenting with acute optic neuropathy"],"prefix":"10.1136","volume":"2015","author":[{"given":"Abhijit Anand","family":"Mohite","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Queen's Hospital, Burton-on-Trent, Staffordshire, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana","family":"Agius-Fernandez","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Queen's Hospital, Burton-on-Trent, Staffordshire, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,7,28]]},"reference":[{"key":"2025082722205412000_2015.jul28_1.bcr2015210081.1","doi-asserted-by":"publisher","DOI":"10.4103\/0028-3886.51275"},{"key":"2025082722205412000_2015.jul28_1.bcr2015210081.2","doi-asserted-by":"publisher","DOI":"10.1007\/s12038-008-0063-2"},{"key":"2025082722205412000_2015.jul28_1.bcr2015210081.3","unstructured":"WHO. Chikungunya. Fact Sheet No 327. Updated October 2014. http:\/\/www.who.int\/mediacentre\/factsheets\/fs327\/en\/ (accessed 25 Jan 2015)."},{"key":"2025082722205412000_2015.jul28_1.bcr2015210081.4","doi-asserted-by":"publisher","DOI":"10.1258\/td.2008.080382"},{"key":"2025082722205412000_2015.jul28_1.bcr2015210081.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2007.03.085"},{"key":"2025082722205412000_2015.jul28_1.bcr2015210081.6","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.125.10.1381"},{"key":"2025082722205412000_2015.jul28_1.bcr2015210081.7","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6702863"},{"key":"2025082722205412000_2015.jul28_1.bcr2015210081.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2007.06.002"},{"key":"2025082722205412000_2015.jul28_1.bcr2015210081.9","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.58.7.1098"},{"key":"2025082722205412000_2015.jul28_1.bcr2015210081.10","doi-asserted-by":"publisher","DOI":"10.4103\/0972-2327.83087"},{"key":"2025082722205412000_2015.jul28_1.bcr2015210081.11","doi-asserted-by":"publisher","DOI":"10.1186\/1869-5760-3-35"},{"key":"2025082722205412000_2015.jul28_1.bcr2015210081.12","doi-asserted-by":"publisher","DOI":"10.3201\/eid1210.060610"},{"key":"2025082722205412000_2015.jul28_1.bcr2015210081.13","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis296"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2015-210081","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T05:21:01Z","timestamp":1756358461000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2015-210081"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,28]]},"references-count":13,"alternative-id":["10.1136\/bcr-2015-210081"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2015-210081","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,28]]}}}