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The controversial topic of the management of acute appendicitis in a febrile patient with neutropaenia is also reviewed and discussed.<\/jats:p>","DOI":"10.1136\/bcr-2015-210347","type":"journal-article","created":{"date-parts":[[2015,10,6]],"date-time":"2015-10-06T04:52:24Z","timestamp":1444107144000},"page":"bcr2015210347","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Acute appendicitis presenting as pneumoperitoneum in a teenage boy undergoing chemotherapy"],"prefix":"10.1136","volume":"2015","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8723-0594","authenticated-orcid":false,"given":"C W Y","family":"Wong","sequence":"first","affiliation":[{"name":"Division of Paediatric Surgery, Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P H Y","family":"Chung","sequence":"additional","affiliation":[{"name":"Division of Paediatric Surgery, Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L C L","family":"Lan","sequence":"additional","affiliation":[{"name":"Division of Paediatric Surgery, Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K K Y","family":"Wong","sequence":"additional","affiliation":[{"name":"Division of Paediatric Surgery, Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,10,6]]},"reference":[{"key":"2025082706572613000_2015.oct06_1.bcr2015210347.1","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0b013e31825c157f"},{"key":"2025082706572613000_2015.oct06_1.bcr2015210347.2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19961001)78:7<1477::AID-CNCR15>3.0.CO;2-X"},{"key":"2025082706572613000_2015.oct06_1.bcr2015210347.3","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1200\/JCO.2000.18.3.463","article-title":"Randomized trial of omeprazole or ranitidine versus placebo in the prevention of chemotherapy-induced gastroduodenal injury","volume":"18","author":"Sartori","year":"2000","journal-title":"J Clin Oncol"},{"key":"2025082706572613000_2015.oct06_1.bcr2015210347.4","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2013-004587"},{"key":"2025082706572613000_2015.oct06_1.bcr2015210347.5","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.38.3.348"},{"key":"2025082706572613000_2015.oct06_1.bcr2015210347.6","doi-asserted-by":"publisher","DOI":"10.1007\/PL00011187"},{"key":"2025082706572613000_2015.oct06_1.bcr2015210347.7","doi-asserted-by":"publisher","DOI":"10.1159\/000356817"},{"key":"2025082706572613000_2015.oct06_1.bcr2015210347.8","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-6757(99)90077-3"},{"key":"2025082706572613000_2015.oct06_1.bcr2015210347.9","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1111\/j.1742-1241.1990.tb10134.x","article-title":"Acute appendicitis associated with pneumoperitoneum","volume":"44","author":"Cizmeli","year":"1990","journal-title":"Br J Clin Pract"},{"key":"2025082706572613000_2015.oct06_1.bcr2015210347.10","first-page":"21","article-title":"Perforated neonatal appendicitis with pneumoperitoneum","volume":"4","author":"Khan","year":"2013","journal-title":"APSP J Case Rep"},{"key":"2025082706572613000_2015.oct06_1.bcr2015210347.11","first-page":"186","article-title":"Perforated appendicitis\u2014a rare cause of pneumoperitoneum","volume":"97","author":"Dosseh","year":"2007","journal-title":"S Afr Med J"},{"key":"2025082706572613000_2015.oct06_1.bcr2015210347.12","first-page":"188","article-title":"Pneumoperitoneum secondary to perforated appendicitis. 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