{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:37:38Z","timestamp":1787017058907,"version":"build-2736575974"},"reference-count":29,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,9,16]]},"abstract":"<jats:p>We describe a case of a 21-year-old primigravida at 36\u2005weeks\u2019 gestation who was admitted to a local hospital because of abdominal pain. She was prescribed a total of six doses of diclofenac 50\u2005mg over 2\u2005days. One day later, there was difficulty registering the fetal heartbeats on cardiotocography. Ultrasound examination revealed a fetus with ascites and pathological flow over the tricuspid valve. The patient was referred to a tertiary centre for fetal medicine. Fetal echocardiography revealed, in addition to ascites and tricuspid regurgitation, a constricted ductus arteriosus, dilated right ventricle and reduced flow in the pulmonary artery. Immediate caesarean section resulted in an excellent neonatal outcome.<\/jats:p>","DOI":"10.1136\/bcr-2015-210473","type":"journal-article","created":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T11:53:34Z","timestamp":1443700414000},"page":"bcr2015210473","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":12,"title":["Prenatal constriction of the ductus arteriosus following maternal diclofenac medication in the third trimester"],"prefix":"10.1136","volume":"2015","author":[{"given":"Karoline","family":"Aker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Brantberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siri Ann","family":"Nyrnes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2015,10,1]]},"reference":[{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.1","doi-asserted-by":"publisher","DOI":"10.1038\/newbio231232a0"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02735557"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.3","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/15.11.2423"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.4","doi-asserted-by":"publisher","DOI":"10.2174\/138920012800166607"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.5","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1G428"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.6","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.me.32.020181.002111"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.7","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.592063"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.acvd.2010.06.006"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.9","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.12.1662"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.10","doi-asserted-by":"publisher","DOI":"10.1071\/RD9910489"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.11","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-012-0461-y"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.12","first-page":"231","article-title":"Severe pulmonary hypertension in a neonate caused by premature closure of the ductus arteriosus following maternal treatment with diclofenac: a case report","volume":"26","author":"Zenker","year":"1998","journal-title":"J Perinat Med"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.13","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1111\/j.1479-828X.1999.tb03456.x","article-title":"Premature in utero closure of the ductus arteriosus following maternal ingestion of sodium diclofenac","volume":"39","author":"Mas","year":"1999","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.14","doi-asserted-by":"publisher","DOI":"10.1159\/000020882"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2004.00319.x"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.16","doi-asserted-by":"publisher","DOI":"10.1159\/000350979"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.17","doi-asserted-by":"publisher","DOI":"10.1002\/uog.2647"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.18","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1038"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.19","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(97)70184-4"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.20","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-012-2114-z"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.21","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-003-1338-3"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.22","doi-asserted-by":"publisher","DOI":"10.1517\/14656566.5.3.571"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.23","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e31828a4b54"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.24","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2014.10.1091"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.25","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.04.019"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.26","first-page":"CD001992","article-title":"Cyclo-oxygenase (COX) inhibitors for treating preterm labour","volume":"6","author":"Reinebrant","year":"2015","journal-title":"Cochrane Database of Syst Rev"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.27","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e6226"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.28","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.75.2.406"},{"key":"2025042707165227000_2015.oct01_2.bcr2015210473.29","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(96)70317-4"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2015-210473","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T10:16:58Z","timestamp":1745749018000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2015-210473"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10,1]]},"references-count":29,"alternative-id":["10.1136\/bcr-2015-210473"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2015-210473","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,10,1]]}}}