{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:02:42Z","timestamp":1756425762186,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,7,28]]},"abstract":"<jats:p>A 22-year-old man presented with a 1-day history of severe abdominal pain. He developed a generalised vesicular rash 12\u2005h prior to admission. On examination, he was maximally tender with peritonism in the lower abdomen. Working diagnosis was perforated appendix and a decision to investigate with CT was made, which showed intra-abdominal haemorrhage likely arising from a ruptured spleen. After a period of observation, he subsequently underwent laparotomy and emergency splenectomy. Viral PCR from vesicular fluid was positive for varicella zoster virus. Viral serology was otherwise negative.<\/jats:p>","DOI":"10.1136\/bcr-2015-210909","type":"journal-article","created":{"date-parts":[[2015,8,13]],"date-time":"2015-08-13T09:39:38Z","timestamp":1439458778000},"page":"bcr2015210909","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Varicella zoster virus infection is an unusual cause of splenic rupture"],"prefix":"10.1136","volume":"2015","author":[{"given":"Laura J","family":"Clifton","sequence":"first","affiliation":[{"name":"Department of General Surgery, Buckinghamshire Healthcare NHS Trust, Aylesbury, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kawaljit Singh","family":"Dhaliwal","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Buckinghamshire Healthcare NHS Trust, Aylesbury, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danah","family":"Saif","sequence":"additional","affiliation":[{"name":"Department of Histopathology, Buckinghamshire Healthcare NHS Trust, High Wycombe, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pepe","family":"Mullerat","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Buckinghamshire Healthcare NHS Trust, Aylesbury, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,8,13]]},"reference":[{"key":"2025082800180038000_2015.aug13_1.bcr2015210909.1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6737"},{"key":"2025082800180038000_2015.aug13_1.bcr2015210909.2","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1471-227X-12-11","article-title":"613 cases of splenic rupture without risk factors or previously diagnosed disease: a systematic review","volume":"12","author":"Aubrey-Bassler","year":"2012","journal-title":"BMC Em Med"},{"key":"2025082800180038000_2015.aug13_1.bcr2015210909.3","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.324.7338.660"},{"key":"2025082800180038000_2015.aug13_1.bcr2015210909.4","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5644.617"},{"key":"2025082800180038000_2015.aug13_1.bcr2015210909.5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.1998.tb04733.x"},{"key":"2025082800180038000_2015.aug13_1.bcr2015210909.6","doi-asserted-by":"publisher","DOI":"10.1097\/01.mej.0000104026.33339.d5"},{"key":"2025082800180038000_2015.aug13_1.bcr2015210909.7","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1995.01430060100020"},{"key":"2025082800180038000_2015.aug13_1.bcr2015210909.8","doi-asserted-by":"crossref","first-page":"b2431","DOI":"10.1136\/bmj.b2431","article-title":"Imaging strategies for detection of urgent conditions in patients with acute abdominal pain: diagnostic accuracy study","volume":"38","author":"Lameris","year":"2009","journal-title":"BMJ"},{"key":"2025082800180038000_2015.aug13_1.bcr2015210909.9","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g1864"},{"key":"2025082800180038000_2015.aug13_1.bcr2015210909.10","doi-asserted-by":"publisher","DOI":"10.1186\/cc12868"},{"key":"2025082800180038000_2015.aug13_1.bcr2015210909.11","unstructured":"Albrecht MA . Treatment of varicella-zoster virus infection: chickenpox. In: Hirsch MS , ed. UpToDate. UpToDate. (accessed 11 Mar 2015)."},{"key":"2025082800180038000_2015.aug13_1.bcr2015210909.12","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-117-5-358"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2015-210909","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:18:08Z","timestamp":1756365488000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2015-210909"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8,13]]},"references-count":12,"alternative-id":["10.1136\/bcr-2015-210909"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2015-210909","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2015,8,13]]}}}