{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T10:31:04Z","timestamp":1762252264181,"version":"3.44.0"},"reference-count":14,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,8,23]]},"abstract":"<jats:p>A 56-year-old Caucasian woman presented with epigastric pain, watery diarrhoea, bloating and flatulence following treatment with duloxetine and venlafaxine for anxiety and depression. Abdominal examination was benign. Blood work revealed haemoglobin of 96\u2005g\/L (115\u2013160\u2005g\/L), iron 6\u2005\u03bcmol\/L (10\u201333\u2005\u03bcmol\/L), transferrin saturation 0.08 (0.20\u20130.55), ferritin 26\u2005\u03bcg\/L (15\u2013180\u2005\u03bcg\/L), albumin 46\u2005g\/L (35\u201350\u2005g\/L), pre-albumin 293\u2005mg\/L (170\u2013370\u2005mg\/L), total IgA 2.64\u2005g\/L (0.78\u20133.58\u2005g\/L) and anti-tTG IgA 5\u2005units (&lt;20\u2005units). Faecal occult blood tests were 3\/3 positive and stool cultures were negative. CT enterography was normal. Colonic biopsy revealed collagenous colitis, while duodenal biopsy showed collagenous sprue with blunted to completely flattened villi and markedly thickened subepithelial collagen table entrapping capillaries and lymphocytes. The patient started a gluten-free diet, loperamide and ferrous gluconate. Her symptoms resolved and a faecal immunochemical test performed 6\u2005months later was negative.<\/jats:p>","DOI":"10.1136\/bcr-2015-211200","type":"journal-article","created":{"date-parts":[[2015,9,7]],"date-time":"2015-09-07T09:38:54Z","timestamp":1441618734000},"page":"bcr2015211200","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Collagenous enterocolitis manifesting as watery diarrhoea and iron-deficiency anaemia"],"prefix":"10.1136","volume":"2015","author":[{"given":"Alan Hoi Lun","family":"Yau","sequence":"first","affiliation":[{"name":"St Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Xiong","sequence":"additional","affiliation":[{"name":"St Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hin Hin","family":"Ko","sequence":"additional","affiliation":[{"name":"St Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,9,7]]},"reference":[{"key":"2025082801115487000_2015.sep07_1.bcr2015211200.1","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1155\/2011\/821976","article-title":"Collagenous sprue","volume":"25","author":"Freeman","year":"2011","journal-title":"Can J Gastroenterol"},{"key":"2025082801115487000_2015.sep07_1.bcr2015211200.2","doi-asserted-by":"publisher","DOI":"10.1111\/den.12007"},{"key":"2025082801115487000_2015.sep07_1.bcr2015211200.3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197012102832401"},{"key":"2025082801115487000_2015.sep07_1.bcr2015211200.4","first-page":"1343","article-title":"Collagenous sprue and ulcerative jejunoileitis in a patient with gluten-induced enteropathy","volume":"116","author":"Guller","year":"1986","journal-title":"Schweiz Med Wochenschr"},{"key":"2025082801115487000_2015.sep07_1.bcr2015211200.5","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181ae2545"},{"key":"2025082801115487000_2015.sep07_1.bcr2015211200.6","first-page":"458","article-title":"Collagenous colitis and ileitis under treatment with duloxetine","volume":"75","author":"Sisman","year":"2012","journal-title":"Acta Gastroenterol Belg"},{"key":"2025082801115487000_2015.sep07_1.bcr2015211200.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.revmed.2008.04.005"},{"key":"2025082801115487000_2015.sep07_1.bcr2015211200.8","first-page":"347","article-title":"Hyposplenism, antiendomysial antibodies and lymphocytic colitis in collagenous sprue","volume":"13","author":"Freeman","year":"1999","journal-title":"Can J Gastroenterol"},{"key":"2025082801115487000_2015.sep07_1.bcr2015211200.9","doi-asserted-by":"crossref","unstructured":"Hunter JM , Lee HJ , Dettrick A , et al . 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