{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:40:03Z","timestamp":1756305603668,"version":"3.44.0"},"reference-count":21,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,8,18]]},"abstract":"<jats:p>A 67-year-old woman with myelodysplastic syndrome (MDS) and transfusional haemosiderosis developed <jats:italic>Salmonella<\/jats:italic> empyema caused by direct extension from splenic abscesses. She was successfully treated with antibiotics, pleural decortication and splenectomy. She had presented with fever after being treated for presumed pneumonia and parapneumonic effusion 2\u2005months prior. CT scan showed splenic abscesses eroding through the diaphragm causing a left pleural empyema. Pleural fluid and spleen bacterial cultures grew <jats:italic>Salmonella enterica<\/jats:italic>. She was treated with 4\u2005weeks of antibiotics and underwent surgical pleural decortication and splenectomy in the same sitting. She made a good postoperative recovery. Patients with severe iron overload are susceptible to various types of bacterial sepsis, including salmonellosis. It is unusual for enteric bacterial such as <jats:italic>Salmonella<\/jats:italic> to present with empyema, and should prompt a search for intra-abdominal infection. Pleural decortication and splenectomy can be performed during the same surgical sitting and can lead to good surgical outcomes.<\/jats:p>","DOI":"10.1136\/bcr-2015-211351","type":"journal-article","created":{"date-parts":[[2015,9,2]],"date-time":"2015-09-02T04:26:29Z","timestamp":1441167989000},"page":"bcr2015211351","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Uncovering what lies beneath a <i>Salmonella enterica<\/i> empyema"],"prefix":"10.1136","volume":"2015","author":[{"given":"Jia Wei","family":"Woo","sequence":"first","affiliation":[{"name":"National University Health Services, Singapore, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John Kit Chung","family":"Tam","sequence":"additional","affiliation":[{"name":"National University Health Services, Singapore, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas Su Gin","family":"Chan","sequence":"additional","affiliation":[{"name":"National University Health Services, Singapore, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shi","family":"Wang","sequence":"additional","affiliation":[{"name":"National University Health Services, Singapore, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lee Shir","family":"Ying","sequence":"additional","affiliation":[{"name":"National University Health Services, Singapore, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,9,2]]},"reference":[{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.1","doi-asserted-by":"publisher","DOI":"10.1080\/00365540500264944"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.2","first-page":"436","article-title":"Splenic abscess: clinical features, microbiologic finding, treatment and outcome","volume":"86","author":"Sangchan","year":"2003","journal-title":"J Med Assoc Thai"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.3","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1080\/00015458.1998.12098414","article-title":"Splenic abscess: a diagnostic and therapeutic challenge","volume":"98","author":"De Bree","year":"1998","journal-title":"Acta Chir Belg"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.4","doi-asserted-by":"publisher","DOI":"10.1378\/chest.127.4.1427"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.5","first-page":"664","article-title":"Clinical manifestation of pulmonary melioidosis in adults","volume":"35","author":"Reechaipichitkul","year":"2004","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.6","first-page":"82","article-title":"Tuberculous empyema","volume":"14","author":"Sahn","year":"1999","journal-title":"Semin Respir Infect"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.7","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-2478(02)00229-8"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.8","doi-asserted-by":"publisher","DOI":"10.1007\/s10534-006-9073-4"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.9","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.284.6315.542"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.10","first-page":"524","article-title":"Impaired neutrophil defense against Yersinia enterocolitica in patients with iron overload who are undergoing dialysis","volume":"111","author":"Cantinieaux","year":"1988","journal-title":"J Lab Clin Med"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.11","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-07-234062"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.12","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v18.i10.1137"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.13","doi-asserted-by":"publisher","DOI":"10.1007\/BF01655272"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.14","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1155\/2004\/801576","article-title":"Isolated splenic vein thrombosis: an unusual cause and review of the literature","volume":"18","author":"Koklu","year":"2004","journal-title":"Can J Gastroenterology"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.15","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-07-551515"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.16","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-83-5-661"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.17","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5799.546"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.18","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6072.1323"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.19","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1590\/S1413-86702002000200005","article-title":"Isolation of Salmonella enterica serotype Worthington from a splenic abscess in a patient with chronic myeloid leukemia","volume":"6","author":"Ghadage","year":"2002","journal-title":"Braz J Infect Dis"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.20","first-page":"567","article-title":"Splenic abscess: diagnosis and management","volume":"49","author":"Ng","year":"2002","journal-title":"Hepatogastroenterology"},{"key":"2025082707253857000_2015.sep02_1.bcr2015211351.21","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2008.08.024"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2015-211351","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:25:48Z","timestamp":1756304748000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2015-211351"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,2]]},"references-count":21,"alternative-id":["10.1136\/bcr-2015-211351"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2015-211351","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2015,9,2]]}}}