{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T10:10:03Z","timestamp":1756375803966,"version":"3.44.0"},"reference-count":8,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,8,18]]},"abstract":"<jats:p>Primary thymic extranodal marginal zone B cell lymphoma (TML) is an extremely rare lymphoma strongly associated with autoimmune disease. We report an exceedingly rare case of TML found in a non-Asian population. TML was found incidentally in a 60-year-old Caucasian woman with a short history of muscle and joint pain. An anterior mediastinal mass was detected by a positron emission tomography-CT (PET-CT) scan and thymectomy was performed. The mass was contained within the thymus with a homogeneous pale cut surface with solid areas. Histologically, the typical morphological and immunophenotypic features of TML were found, with a prominent lymphoid infiltrate comprising of small-to-medium-sized neoplastic lymphocytes, plasmacytic differentiation and a distorted thymic epithelial network. Postoperative follow-up has indicated an associated undifferentiated connective tissue disease (UCTD) with features of systemic lupus erythaematosus.<\/jats:p>","DOI":"10.1136\/bcr-2015-211469","type":"journal-article","created":{"date-parts":[[2015,9,3]],"date-time":"2015-09-03T10:33:00Z","timestamp":1441276380000},"page":"bcr2015211469","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Primary thymic extranodal marginal zone B cell lymphoma as an incidental finding in a Caucasian woman"],"prefix":"10.1136","volume":"2015","author":[{"given":"Jeanette","family":"Krogh Petersen","sequence":"first","affiliation":[{"name":"Department of Pathology, Odense University Hospital, Odense, Fyn, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas Stauffer","family":"Larsen","sequence":"additional","affiliation":[{"name":"Department of Hematology, Odense University Hospital, Odense, Fyn, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael Boe","family":"M\u00f8ller","sequence":"additional","affiliation":[{"name":"Department of Pathology, Odense University Hospital, Odense, Fyn, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Stahlberg","sequence":"additional","affiliation":[{"name":"Department of Pathology, Odense University Hospital, Odense, Fyn, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,9,3]]},"reference":[{"key":"2025082802562386000_2015.sep03_1.bcr2015211469.1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2003.18.6.897"},{"key":"2025082802562386000_2015.sep03_1.bcr2015211469.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)62569-2"},{"key":"2025082802562386000_2015.sep03_1.bcr2015211469.3","unstructured":"Chan ACL , Chan JKC , Inagaki H , et al . Thymic extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT). In: Travis WD , Brambilla E , Muller-Hermelink HK , et al ., eds. World Health Organization classification of tumours; tumours of the lung, pleura, thymus and heart. IARC Press, 2004:225\u20136."},{"key":"2025082802562386000_2015.sep03_1.bcr2015211469.4","doi-asserted-by":"publisher","DOI":"10.1007\/s11748-008-0237-8"},{"key":"2025082802562386000_2015.sep03_1.bcr2015211469.5","doi-asserted-by":"publisher","DOI":"10.1309\/H7V2-G9L4-GR9G-8GK0"},{"key":"2025082802562386000_2015.sep03_1.bcr2015211469.6","unstructured":"Isaacson PG , Chott A , Nakamura S , et al . Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma). In: Jaffe ES , Harris NL , Stein H , et al , eds. World Health Organization classification of tumours; tumours of haematopoietic and lymphoid tissue. IARC Press, 2008:214\u201317."},{"key":"2025082802562386000_2015.sep03_1.bcr2015211469.7","doi-asserted-by":"publisher","DOI":"10.1080\/02841860500531682"},{"key":"2025082802562386000_2015.sep03_1.bcr2015211469.8","doi-asserted-by":"publisher","DOI":"10.1309\/G3AC-P7K8-2JNK-8C3U"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2015-211469","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:56:27Z","timestamp":1756374987000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2015-211469"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,3]]},"references-count":8,"alternative-id":["10.1136\/bcr-2015-211469"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2015-211469","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2015,9,3]]}}}