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Establishing such diagnoses in a timely manner is imperative for the child, parents and clinicians. The clinical course of these twins reflects the unpredictable prognosis associated with the diagnosis of mosaic trisomy 18, and emphasises the challenges that can be encountered when counselling parents.<\/jats:p>","DOI":"10.1136\/bcr-2015-211587","type":"journal-article","created":{"date-parts":[[2015,11,11]],"date-time":"2015-11-11T07:07:55Z","timestamp":1447225675000},"page":"bcr2015211587","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Phenotypic extremes in liveborn monozygotic twins with mosaic Edwards syndrome"],"prefix":"10.1136","volume":"2015","author":[{"given":"Neidin","family":"Bussmann","sequence":"first","affiliation":[{"name":"Department of Neonatology, Cork University Maternity Hospital (CUMH), Cork, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katie","family":"Cunningham","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Cork University Maternity Hospital (CUMH), Cork, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Green","sequence":"additional","affiliation":[{"name":"Department of Clinical Genetics, OLCHC, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C Anthony","family":"Ryan","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Child Health, University College Cork, Cork, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,11,11]]},"reference":[{"key":"2025082707092944000_2015.nov11_1.bcr2015211587.1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-7-81"},{"key":"2025082707092944000_2015.nov11_1.bcr2015211587.2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.8.3.392"},{"key":"2025082707092944000_2015.nov11_1.bcr2015211587.3","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1002\/ajmg.a.31535","article-title":"Phenotypic spectrum of mosaic trisomy 18: two new patients, a literature review, and counseling issues","volume":"143A","author":"Tucker","year":"2007","journal-title":"Am J Med Genet A"},{"key":"2025082707092944000_2015.nov11_1.bcr2015211587.4","unstructured":"Central Statistics Office on behalf of Department of Health and Children: Report on Vital Statistics, Tuarascail ar Staidreamh Beatha. 2004."},{"key":"2025082707092944000_2015.nov11_1.bcr2015211587.5","unstructured":"Royal College of Obstetrics and Gynaecologists. 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