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Although LCNEC of the head and neck is still classified as an atypical carcinoid, there is increasing evidence it is a distinct clinicohistopathological entity that carries an especially poor prognosis. Currently, there is a paucity of data to guide treatment of this rare malignancy.<\/jats:p>","DOI":"10.1136\/bcr-2015-211908","type":"journal-article","created":{"date-parts":[[2015,12,29]],"date-time":"2015-12-29T05:18:18Z","timestamp":1451366298000},"page":"bcr2015211908","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Hypopharyngeal large cell neuroendocrine carcinoma"],"prefix":"10.1136","volume":"2015","author":[{"given":"Wei-I","family":"Lee","sequence":"first","affiliation":[{"name":"Austin Health, Melbourne, Heidelberg, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malaka","family":"Ameratunga","sequence":"additional","affiliation":[{"name":"Department of Oncology, Austin Health, Melbourne, Heidelberg, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin","family":"du Plessis","sequence":"additional","affiliation":[{"name":"Department of Pathology, Austin Health, Melbourne, Heidelberg, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Gan","sequence":"additional","affiliation":[{"name":"Department of Oncology, Austin Health, Melbourne, Heidelberg, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,12,29]]},"reference":[{"key":"2025082702360165000_2015.dec28_1.bcr2015211908.1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11105"},{"key":"2025082702360165000_2015.dec28_1.bcr2015211908.2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-014-3090-7"},{"key":"2025082702360165000_2015.dec28_1.bcr2015211908.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2006.01.002"},{"key":"2025082702360165000_2015.dec28_1.bcr2015211908.4","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-013-2554-5"},{"key":"2025082702360165000_2015.dec28_1.bcr2015211908.5","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199106000-00003"},{"key":"2025082702360165000_2015.dec28_1.bcr2015211908.6","doi-asserted-by":"crossref","unstructured":"Travis WD , Colby TV , Corrin B , et al . 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