{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,3]],"date-time":"2025-08-03T22:51:15Z","timestamp":1754261475260,"version":"3.40.4"},"reference-count":19,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,10,15]]},"abstract":"<jats:p>Right-sided infective endocarditis (RIE) is commonly due to<jats:italic>Staphylococcus aureus<\/jats:italic>and often involves the tricuspid valve (TV). A 31-year-old man with prior intravenous drug use presented with substernal pain, cough, dyspnoea and fever. Examination revealed a febrile, tachycardic male with peripheral infective endocarditis stigmata and right-heart failure. Laboratory parameters demonstrated leucocytosis, lactic acidosis and methicillin-resistant<jats:italic>S. aureus<\/jats:italic>(MRSA) bacteraemia. Echocardiography demonstrated multiple TV echodensities and chest imaging confirmed septic emboli. The MRSA species demonstrated \u2018vancomycin-creep\u2019, necessitating therapy with daptomycin and ceftaroline. Owing to persistent bacteraemia and septic shock, the patient underwent TV surgery, but continued to have a poor postoperative course with subsequent death. Indications for surgical therapy of RIE are limited to the European guidelines and most data are extrapolated from left-heart disease. MRSA exhibiting vancomycin-creep portends a poorer prognosis and requires aggressive therapy. We advocate the use of ceftaroline salvage therapy with daptomycin, pending further trials.<\/jats:p>","DOI":"10.1136\/bcr-2015-211974","type":"journal-article","created":{"date-parts":[[2016,2,15]],"date-time":"2016-02-15T18:47:30Z","timestamp":1455562050000},"page":"bcr2015211974","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Tricuspid and mitral endocarditis due to methicillin-resistant<i>Staphylococcus aureus<\/i>exhibiting vancomycin-creep phenomenon"],"prefix":"10.1136","volume":"2015","author":[{"given":"Pranathi Rao","family":"Sundaragiri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saraschandra","family":"Vallabhajosyula","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toufik","family":"Mahfood Haddad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dennis J","family":"Esterbrooks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,11,3]]},"reference":[{"key":"2025042707331835000_2015.nov03_1.bcr2015211974.1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.162.1.90"},{"key":"2025042707331835000_2015.nov03_1.bcr2015211974.2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2005.067256"},{"key":"2025042707331835000_2015.nov03_1.bcr2015211974.3","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1945.02860030001001"},{"key":"2025042707331835000_2015.nov03_1.bcr2015211974.4","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-12-1364"},{"key":"2025042707331835000_2015.nov03_1.bcr2015211974.5","doi-asserted-by":"publisher","DOI":"10.5761\/atcs.cr.11.01846"},{"key":"2025042707331835000_2015.nov03_1.bcr2015211974.6","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2008.603"},{"key":"2025042707331835000_2015.nov03_1.bcr2015211974.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2013.01.010"},{"key":"2025042707331835000_2015.nov03_1.bcr2015211974.8","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0000000000000101"},{"key":"2025042707331835000_2015.nov03_1.bcr2015211974.9","doi-asserted-by":"publisher","DOI":"10.1097\/MCC.0b013e3283578968"},{"key":"2025042707331835000_2015.nov03_1.bcr2015211974.10","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5520(01)00008-3"},{"key":"2025042707331835000_2015.nov03_1.bcr2015211974.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.02.536"},{"key":"2025042707331835000_2015.nov03_1.bcr2015211974.12","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2003.029868"},{"key":"2025042707331835000_2015.nov03_1.bcr2015211974.13","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5520(01)00006-X"},{"key":"2025042707331835000_2015.nov03_1.bcr2015211974.14","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(97)00117-3"},{"key":"2025042707331835000_2015.nov03_1.bcr2015211974.15","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp285"},{"key":"2025042707331835000_2015.nov03_1.bcr2015211974.16","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.773598"},{"key":"2025042707331835000_2015.nov03_1.bcr2015211974.17","first-page":"653582","article-title":"Daptomycin failure for treatment of pulmonary septic emboli in native tricuspid and mitral valve methicillin-resistant Staphylococcus aureus endocarditis","volume":"2013","author":"Zainah","year":"2013","journal-title":"Case Rep Infect Dis"},{"key":"2025042707331835000_2015.nov03_1.bcr2015211974.18","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2014.05.061"},{"key":"2025042707331835000_2015.nov03_1.bcr2015211974.19","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dku378"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2015-211974","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T14:33:25Z","timestamp":1745764405000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2015-211974"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,3]]},"references-count":19,"alternative-id":["10.1136\/bcr-2015-211974"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2015-211974","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2015,11,3]]}}}