{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T23:19:03Z","timestamp":1762298343305,"version":"3.44.0"},"reference-count":15,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,11,26]]},"abstract":"<jats:p>A 33-year-old man developed profound sudden onset right-sided hearing loss with tinnitus and vertigo, within 24\u2005h of pretravel rabies vaccination. There was no history of upper respiratory tract infection, systemic illness, ototoxic medication or trauma, and normal otoscopic examination. Pure tone audiograms (PTA) demonstrated right-sided sensorineural hearing loss (thresholds 90\u2013100\u2005dB) and normal left-sided hearing. MRI internal acoustic meatus, viral serology (hepatitis B, C, HIV and cytomegalovirus) and syphilis screen were normal. Positive Epstein-Barr virus IgG, viral capsid IgG and anticochlear antibodies (anti-HSP-70) were noted. Initial treatment involved a course of high-dose oral prednisolone and acyclovir. Repeat PTAs after 12\u2005days of treatment showed a small improvement in hearing thresholds. Salvage intratympanic steroid injections were attempted but failed to improve hearing further. Sudden onset sensorineural hearing loss (SSNHL) is an uncommon but frightening experience for patients. This is the first report of SSNHL following rabies immunisation in an adult.<\/jats:p>","DOI":"10.1136\/bcr-2015-211977","type":"journal-article","created":{"date-parts":[[2015,12,15]],"date-time":"2015-12-15T07:57:57Z","timestamp":1450166277000},"page":"bcr2015211977","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":19,"title":["Sudden onset unilateral sensorineural hearing loss after rabies vaccination"],"prefix":"10.1136","volume":"2015","author":[{"given":"Saleh","family":"Okhovat","sequence":"first","affiliation":[{"name":"Department of ENT, West Scotland Deanery, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Fox","sequence":"additional","affiliation":[{"name":"Department of ENT, Northwick Park Hospital, London, Harrow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Magill","sequence":"additional","affiliation":[{"name":"Department of ENT, St Mary's Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antony","family":"Narula","sequence":"additional","affiliation":[{"name":"Department of ENT, St Mary's Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,12,15]]},"reference":[{"key":"2025082722435548000_2015.dec15_1.bcr2015211977.1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599812436449"},{"key":"2025082722435548000_2015.dec15_1.bcr2015211977.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2010.05.018"},{"key":"2025082722435548000_2015.dec15_1.bcr2015211977.3","doi-asserted-by":"publisher","DOI":"10.1136\/adc.69.1.153"},{"key":"2025082722435548000_2015.dec15_1.bcr2015211977.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0385-8146(97)10013-X"},{"key":"2025082722435548000_2015.dec15_1.bcr2015211977.5","doi-asserted-by":"crossref","first-page":"327","DOI":"10.5152\/balkanmedj.2013.8465","article-title":"Sudden hearing loss after rabies vaccination","volume":"30","author":"G\u00fc\u00e7l\u00fc","year":"2013","journal-title":"Balkan Med J"},{"key":"2025082722435548000_2015.dec15_1.bcr2015211977.6","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.3268.298"},{"key":"2025082722435548000_2015.dec15_1.bcr2015211977.7","unstructured":"Veeraraghavan N . Pasteur Institute of Southern India Coonoor. Scientific Report 1968 1 Rabies; 1969, 35e80."},{"key":"2025082722435548000_2015.dec15_1.bcr2015211977.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2007.02.075"},{"key":"2025082722435548000_2015.dec15_1.bcr2015211977.9","first-page":"279","article-title":"Peripheral facial paralysis and post-antirabies-vaccination polyneuroradiculitis","volume":"78","author":"Cr\u00e9mieux","year":"1978","journal-title":"Acta Neurol Belg"},{"key":"2025082722435548000_2015.dec15_1.bcr2015211977.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmaid.2011.12.005"},{"key":"2025082722435548000_2015.dec15_1.bcr2015211977.11","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-008-0801-y"},{"key":"2025082722435548000_2015.dec15_1.bcr2015211977.12","doi-asserted-by":"publisher","DOI":"10.1097\/01.moo.0000136101.95662.aa"},{"key":"2025082722435548000_2015.dec15_1.bcr2015211977.13","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199512000-00016"},{"key":"2025082722435548000_2015.dec15_1.bcr2015211977.14","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200310000-00020"},{"key":"2025082722435548000_2015.dec15_1.bcr2015211977.15","first-page":"352","article-title":"Intratympanic steroid therapy for treatment of idiopathic sudden sensorineural hearing loss","volume":"111","author":"Bear","year":"2014","journal-title":"Mo Med"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2015-211977","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T05:44:04Z","timestamp":1756359844000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2015-211977"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,15]]},"references-count":15,"alternative-id":["10.1136\/bcr-2015-211977"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2015-211977","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2015,12,15]]}}}