{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T10:13:55Z","timestamp":1777544035738,"version":"3.51.4"},"reference-count":23,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,11,8]]},"abstract":"<jats:p>Transverse myelitis (TM) with systemic lupus erythematosus (SLE) has been linked to the presence of autoantibodies (eg, antiaquaporin 4 (AQP4) and anticardiolipin (aCL)) and SLE-induced secondary vasculitis, but the aetiology remains incompletely understood. A 48-year-old Japanese man with a 6-year history of poorly controlled SLE had stopped glucocorticoid therapy 1\u2005year before admission. 3\u2005days before admission, he developed flaccid paraplegia. Spinal MRI showed a longitudinally hyperintense T2 grey matter lesion from the level of Th4 to the conus medullaris, which was considered longitudinally extensive TM (LETM). We administered steroid pulse therapy (methyl-prednisolone 1000\u2005mg\/day) for 3\u2005days and prednisolone 50\u2005mg\/day. The patient's flaccid paralysis gradually improved. We concluded that the patient's TM was caused by SLE flare-up, even though we could not completely rule out antiphospholipid syndrome. SLE myelitis is relatively rare and many aetiologies are possible for TM in SLE.<\/jats:p>","DOI":"10.1136\/bcr-2015-212112","type":"journal-article","created":{"date-parts":[[2015,11,26]],"date-time":"2015-11-26T11:52:31Z","timestamp":1448538751000},"page":"bcr2015212112","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Longitudinally extensive transverse myelitis with anti-NMDA receptor antibodies during a systemic lupus erythematosus flare-up"],"prefix":"10.1136","volume":"2015","author":[{"given":"Kentarou","family":"Takei","sequence":"first","affiliation":[{"name":"Department of Neurology, Osaki Citizens\u2019 Hospital, Osaki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mineshige","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Neurology, Osaki Citizens\u2019 Hospital, Osaki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masashi","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Neurology, Osaki Citizens\u2019 Hospital, Osaki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Osaki Citizens\u2019 Hospital, Osaki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,11,26]]},"reference":[{"key":"2025082707322156000_2015.nov26_1.bcr2015212112.1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199904)42:4<599::AID-ANR2>3.0.CO;2-F"},{"key":"2025082707322156000_2015.nov26_1.bcr2015212112.2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.59.2.120"},{"key":"2025082707322156000_2015.nov26_1.bcr2015212112.3","first-page":"446","article-title":"Longitudinal involvement of the spinal cord in a patient with lupus related transverse myelitis","volume":"26","author":"Deodhar","year":"1999","journal-title":"J Rheumatol"},{"key":"2025082707322156000_2015.nov26_1.bcr2015212112.4","doi-asserted-by":"publisher","DOI":"10.1177\/0961203314547795"},{"key":"2025082707322156000_2015.nov26_1.bcr2015212112.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2009.05.001"},{"key":"2025082707322156000_2015.nov26_1.bcr2015212112.6","doi-asserted-by":"publisher","DOI":"10.1002\/art.10187"},{"key":"2025082707322156000_2015.nov26_1.bcr2015212112.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2008.09.002"},{"key":"2025082707322156000_2015.nov26_1.bcr2015212112.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2015.01.002"},{"key":"2025082707322156000_2015.nov26_1.bcr2015212112.9","doi-asserted-by":"crossref","unstructured":"Tono T , Nagai T , Hoshiyama T , et al . 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