{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:16:18Z","timestamp":1756383378388,"version":"3.44.0"},"reference-count":5,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,8,31]]},"abstract":"<jats:p>Olmesartan use has been associated with chronic diarrhoea and weight loss due to severe sprue-like enteropathy, yet this is still not well known among clinicians. We present the unique case of an 84-year-old Filipino woman diagnosed with olmesartan-induced sprue-like enteropathy after an extensive work up for chronic diarrhoea, and without improvement despite multiple empiric treatments for nearly 15\u2005months. Withdrawal of olmesartan resulted in clinical and histological improvement. This case provides further evidence for olmesartan-induced sprue-like enteropathy, and emphasises the importance of its awareness and recognition among gastroenterologists and primary care physicians alike.<\/jats:p>","DOI":"10.1136\/bcr-2015-212318","type":"journal-article","created":{"date-parts":[[2015,9,14]],"date-time":"2015-09-14T03:18:49Z","timestamp":1442200729000},"page":"bcr2015212318","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["An atypical case of chronic diarrhoea: olmesartan-induced sprue-like enteropathy"],"prefix":"10.1136","volume":"2015","author":[{"given":"Dhaval K","family":"Naik","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, University of Florida, Gainesville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew G","family":"Martelli","sequence":"additional","affiliation":[{"name":"Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Hernandez Gonzalo","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Florida, Gainesville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anil K","family":"Sharma","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition, University of Florida College of Medicine, Gainesville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davinderbir","family":"Pannu","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition, University of Florida College of Medicine, Gainesville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,9,14]]},"reference":[{"unstructured":"United States Food and Drug Administration. FDA Drug Safety Communication: FDA approves label changes to include intestinal problems (sprue-like enteropathy) linked to blood pressure medicine olmesartan medoxomil. 3 July 2013. http:\/\/www.fda.gov\/Drugs\/DrugSafety\/ucm359477.htm (accessed 14 Jan 2015).","key":"2025082804351922000_2015.sep13_1.bcr2015212318.1"},{"doi-asserted-by":"publisher","key":"2025082804351922000_2015.sep13_1.bcr2015212318.2","DOI":"10.1016\/j.mayocp.2012.06.003"},{"doi-asserted-by":"publisher","key":"2025082804351922000_2015.sep13_1.bcr2015212318.3","DOI":"10.1038\/ajg.2013.45"},{"doi-asserted-by":"publisher","key":"2025082804351922000_2015.sep13_1.bcr2015212318.4","DOI":"10.1111\/apt.12780"},{"doi-asserted-by":"publisher","key":"2025082804351922000_2015.sep13_1.bcr2015212318.5","DOI":"10.1111\/apt.12937"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2015-212318","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:35:29Z","timestamp":1756380929000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2015-212318"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,14]]},"references-count":5,"alternative-id":["10.1136\/bcr-2015-212318"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2015-212318","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2015,9,14]]}}}