{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T04:02:22Z","timestamp":1745812942934,"version":"3.40.4"},"reference-count":29,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,9,12]]},"abstract":"<jats:p>An 11-year-old boy was admitted with fever followed by convulsions. He had developed aphasia subsequent to this illness. His birth history was unremarkable, and he had normal growth and development including of language, hearing and vision. His neurological examination was normal except for aphasia. Investigations including cerebrospinal fluid study and MRI were normal. However, EEG was abnormal and the boy was diagnosed as a case of Landau-Kleffner syndrome (LKS) and treated with sodium valproate, levetiracetam and steroids. He responded well to treatment and has been on follow-up for the last 4\u2005months. We present this case of LKS to increase awareness about early diagnosis and to highlight the importance of appropriate management for a better outcome.<\/jats:p>","DOI":"10.1136\/bcr-2015-212333","type":"journal-article","created":{"date-parts":[[2015,9,29]],"date-time":"2015-09-29T11:32:46Z","timestamp":1443526366000},"page":"bcr2015212333","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Landau-Kleffner syndrome: an uncommon dealt with case in Southeast Asia"],"prefix":"10.1136","volume":"2015","author":[{"given":"Naresh","family":"Motwani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suhaim","family":"Afsar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nachiket S","family":"Dixit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nitin","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,9,29]]},"reference":[{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.7.8.523"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.2","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1469-5812.2005.00134.x-i1","article-title":"The Landau-Kleffner syndrome","volume":"1","author":"Pearl","year":"2001","journal-title":"Epilepsy Curr"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.3","first-page":"908","article-title":"Landau Kleffner syndrome","volume":"35","author":"Bhatia","year":"1995","journal-title":"Indian Pediatr"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.4","doi-asserted-by":"publisher","DOI":"10.1016\/0887-8994(93)90010-A"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1989.tb05473.x"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.6","first-page":"584","article-title":"Landau Kleffner syndrome in cerebral cysticercosis","volume":"31","author":"Bhatia","year":"1994","journal-title":"Indian Pediatr"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.7","first-page":"306","article-title":"Epileptic aphasia (Landau-Kleffner syndrome) secondary to progressive encephalitis","volume":"40","author":"Bicknese","year":"1996","journal-title":"Ann Neurol"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.8","doi-asserted-by":"publisher","DOI":"10.1016\/S0387-7604(99)00028-5"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.9","first-page":"337","article-title":"Landau-Kleffner syndrome\u2014epileptic aphasia in children\u2014possible role of Toxoplasma gondii infection","volume":"29","author":"Michalowicz","year":"1988\u20131989","journal-title":"Acta Paediatr Hung"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.10","doi-asserted-by":"publisher","DOI":"10.1016\/0887-8994(93)90069-O"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.11","doi-asserted-by":"publisher","DOI":"10.1016\/S1071-9091(95)80007-7"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.12","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1097\/00004691-199107010-00005","article-title":"Acquired epileptiform aphasia in children (Landau-Kleffner syndrome)","volume":"9","author":"Deonna","year":"1991","journal-title":"J Clin Neurophysiol"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.13","unstructured":"Beaumanoir A . The Landau-Kleffner syndrome. In: Roger J , Dravet C , Bureau M , et al ., eds. Epileptic syndromes in infancy, childhood, and adolescence. John Libbey Eurotext, 1985:81\u2013191."},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1990.tb05517.x"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.15","first-page":"457","article-title":"Vigabatrin in the Landau-Kleffner syndrome","volume":"35","author":"Appleton","year":"1993","journal-title":"Dev Med Child Neurol"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.16","doi-asserted-by":"publisher","DOI":"10.1016\/0920-1211(94)00073-6"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1997.tb01740.x"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.18","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1991.tb05115.x"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.2000.tb00257.x"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.20","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1989.70.2.0231"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.21","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/122.3.561"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.22","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1111\/j.1469-8749.1985.tb03793.x","article-title":"Age of onset and outcome in \u201cacquired aphasia with convulsive disorder\u201d (Landau Kleffner syndrome)","volume":"27","author":"Bishop","year":"1985","journal-title":"Dev Med Child Neurol"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.23","unstructured":"Clevrie JJ . Epileptic seizures and epilepsies in childhood. In: Swash M , Oxbury J , eds. Clinical neurology. Edinburgh: Churchill Livingstone, 1991:233\u201354."},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.24","first-page":"212","article-title":"Landau-Kleffner syndrome: a case report","volume":"50","author":"Raybarman","year":"2002","journal-title":"Neurol India"},{"key":"2025042707141144000_2015.sep29_1.bcr2015212333.25","unstructured":"Beaumanoir A. The landau kleffner syndrome. In: Roger J et al. eds. Epileptic syndromes in infancy, childhood and adolescence. 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The eponym \u2018Landau-Kleffner syndrome\u2019 should not be restricted to childhood\u2014acquired aphasia with epilepsy. In: Beaumanour A , Bureau M , Deonna T , et al ., eds. Continuous spikes and waves during slow sleep electrical status epilepticus during slow sleep. London: John Libbey Eurotext, 1995:57\u201362."}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2015-212333","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T14:14:21Z","timestamp":1745763261000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2015-212333"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,29]]},"references-count":29,"alternative-id":["10.1136\/bcr-2015-212333"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2015-212333","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2015,9,29]]}}}