{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T22:40:44Z","timestamp":1781304044257,"version":"3.54.1"},"reference-count":10,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,11,11]]},"abstract":"<jats:p>Systemic lupus erythaematosus (SLE) is known to involve the reticuloendothelial system, but spontaneous splenic rupture (SSR) in the context of the disease is a very rare complication. We observed a 61-year-old woman with an unremarkable previous medical history who presented with SSR and underwent an emergency splenectomy. The histopathological analysis of the specimen revealed signs of vasculitis. On review of symptoms with the patient, a history of oligoarthralgia, photosensitivity, xerostomia and Raynaud phenomenon was elicited. Laboratory investigations revealed lymphopaenia, mild proteinuria and positive antinuclear and anti-dsDNA antibodies. The patient was started on hydroxychloroquine and the disease has since remained silent. This article addresses the rare association between SLE and SSR.<\/jats:p>","DOI":"10.1136\/bcr-2015-212531","type":"journal-article","created":{"date-parts":[[2015,11,30]],"date-time":"2015-11-30T19:18:50Z","timestamp":1448911130000},"page":"bcr2015212531","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Systemic lupus erythaematosus presenting as spontaneous splenic rupture"],"prefix":"10.1136","volume":"2015","author":[{"given":"Ant\u00f3nio Jos\u00e9","family":"Cruz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Castro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2015,11,27]]},"reference":[{"key":"2025042707434386000_2015.nov27_1.bcr2015212531.1","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1002\/bjs.7052","article-title":"Systematic review of atraumatic splenic rupture","volume":"97","author":"Khan","year":"2010","journal-title":"Br J Surg"},{"key":"2025042707434386000_2015.nov27_1.bcr2015212531.2","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-011-1934-8"},{"key":"2025042707434386000_2015.nov27_1.bcr2015212531.3","doi-asserted-by":"publisher","DOI":"10.1191\/096120301701548535"},{"key":"2025042707434386000_2015.nov27_1.bcr2015212531.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0049-0172(97)80013-3"},{"key":"2025042707434386000_2015.nov27_1.bcr2015212531.5","doi-asserted-by":"publisher","DOI":"10.1053\/sarh.2002.30636"},{"key":"2025042707434386000_2015.nov27_1.bcr2015212531.6","first-page":"712","article-title":"Spontaneous rupture of the spleen: a rare complication in a patient with lupus nephritis on hemodialysis","volume":"21","author":"Nadri","year":"2010","journal-title":"Saudi J Kidney Dis Transpl"},{"key":"2025042707434386000_2015.nov27_1.bcr2015212531.7","first-page":"1991","article-title":"Splenic rupture in the course of SLE","volume":"26","author":"Zimmerman-Gorska","year":"1971","journal-title":"Pol Tyg Lek"},{"key":"2025042707434386000_2015.nov27_1.bcr2015212531.8","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1976.03270110047031"},{"key":"2025042707434386000_2015.nov27_1.bcr2015212531.9","first-page":"2344","article-title":"Spontaneous rupture of the spleen in a patient with systemic lupus erythematosus","volume":"22","author":"Tolaymat","year":"1995","journal-title":"J Rheumatol"},{"key":"2025042707434386000_2015.nov27_1.bcr2015212531.10","first-page":"273","article-title":"Pathologic diagnosis of spontaneous splenic rupture in systemic lupus erythematosus","volume":"6","author":"Li","year":"2013","journal-title":"Int J Clin Exp Pathol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2015-212531","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T14:43:56Z","timestamp":1745765036000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2015-212531"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,27]]},"references-count":10,"alternative-id":["10.1136\/bcr-2015-212531"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2015-212531","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,11,27]]}}}