{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:10:02Z","timestamp":1756289402292,"version":"3.44.0"},"reference-count":13,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,11,7]]},"abstract":"<jats:p>An asymptomatic 40-year-old para 1 black African woman with pre-existing hypertension and a booking blood pressure of 120\/80\u2005mm\u2005Hg, was admitted with superimposed preeclampsia diagnosed because of worsening hypertension and significant proteinuria at 27+5\u2005weeks gestation. Antenatally, her blood pressure was controlled with labetalol, and blood tests including serum creatinine were within normal limits for pregnancy. Three days later, the patient developed severe hypertension despite treatment, and reported sudden onset severe shortness of breath; oxygen saturations on air dropped to 93%. Auscultation revealed widespread crepitations leading to a working diagnosis of pulmonary oedema. Despite appropriate management, respiratory function continued to deteriorate and she required intubation, ventilation and emergency caesarean section under general anaesthesia. A live male infant was delivered floppy and was intubated and resuscitated. He awaits discharge home on oxygen. The mother's pulmonary oedema resolved postpartum. Echocardiogram showed left ventricular hypertrophy but normal left ventricular function and the patient's hypertension is being controlled on medication.<\/jats:p>","DOI":"10.1136\/bcr-2015-212751","type":"journal-article","created":{"date-parts":[[2015,11,25]],"date-time":"2015-11-25T08:57:35Z","timestamp":1448441855000},"page":"bcr2015212751","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Fulminant antenatal pulmonary oedema in a woman with hypertension and superimposed preeclampsia"],"prefix":"10.1136","volume":"2015","author":[{"given":"Yukiko","family":"Kubota-Sjogren","sequence":"first","affiliation":[{"name":"Women's Health Academic Centre, King's College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Nelson-Piercy","sequence":"additional","affiliation":[{"name":"Women's Directorate Office, 10th floor North Wing, St Thomas' Hospital Guy's and St Thomas\u2019 NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,11,25]]},"reference":[{"key":"2025082702280056000_2015.nov25_1.bcr2015212751.1","unstructured":"NICE clinical guideline 107: hypertension in pregnancy, NHS Evid. 2011. https:\/\/www.nice.org.uk\/Guidance\/CG107"},{"key":"2025082702280056000_2015.nov25_1.bcr2015212751.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2005.00565.x"},{"key":"2025082702280056000_2015.nov25_1.bcr2015212751.3","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.120279"},{"key":"2025082702280056000_2015.nov25_1.bcr2015212751.4","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(87)90135-9"},{"key":"2025082702280056000_2015.nov25_1.bcr2015212751.5","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(02)02733-3"},{"key":"2025082702280056000_2015.nov25_1.bcr2015212751.6","unstructured":"WHO recommendations for prevention and treatment of pre-eclampsia and eclampsia. 2011. http:\/\/www.who.int\/reproductivehealth\/publications\/maternal_perinatal_health\/9789241548335\/en\/"},{"key":"2025082702280056000_2015.nov25_1.bcr2015212751.7","doi-asserted-by":"crossref","first-page":"717","DOI":"10.7196\/SAMJ.4424","article-title":"Maternal deaths associated with eclampsia in South Africa: lessons to learn from the confidential enquiries into maternal deaths, 2005\u20132007","volume":"100","author":"Moodley","year":"2010","journal-title":"S Afr Med J"},{"key":"2025082702280056000_2015.nov25_1.bcr2015212751.8","doi-asserted-by":"crossref","first-page":"385","DOI":"10.2217\/WHE.14.32","article-title":"Management of hypertensive disorders in pregnancy","volume":"10","author":"Moussa","year":"2015","journal-title":"Womens Health (Lond Engl)"},{"key":"2025082702280056000_2015.nov25_1.bcr2015212751.9","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181a45b25"},{"key":"2025082702280056000_2015.nov25_1.bcr2015212751.10","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g2301"},{"key":"2025082702280056000_2015.nov25_1.bcr2015212751.11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2012.07055.x"},{"key":"2025082702280056000_2015.nov25_1.bcr2015212751.12","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.003664"},{"key":"2025082702280056000_2015.nov25_1.bcr2015212751.13","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/S1701-2163(15)30383-2","article-title":"The Pulmonary Edema Preeclampsia Evaluation (PEPE) Study","volume":"36","author":"Gandhi","year":"2014","journal-title":"J Obs Gynaecol Can"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2015-212751","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T09:28:09Z","timestamp":1756286889000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2015-212751"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,25]]},"references-count":13,"alternative-id":["10.1136\/bcr-2015-212751"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2015-212751","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2015,11,25]]}}}