{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T15:10:03Z","timestamp":1745766603375,"version":"3.40.4"},"reference-count":13,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2015,10,29]]},"abstract":"<jats:p>We report a case of a 47-year-old man who presented with hepatosplenomegaly, anaemia and massive splenic infarct. A series of investigations led us to a diagnosis of atypical chronic myeloid leucaemia, a rare variety of a mixed myelodysplastic\/myeloproliferative neoplasm. This is the first case of atypical CML presenting with massive splenic infarction.<\/jats:p>","DOI":"10.1136\/bcr-2015-212821","type":"journal-article","created":{"date-parts":[[2015,11,12]],"date-time":"2015-11-12T15:17:32Z","timestamp":1447341452000},"page":"bcr2015212821","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Atypical CML with massive splenic infarct: an extremely rare presentation"],"prefix":"10.1136","volume":"2015","author":[{"given":"Dhrubajyoti","family":"Bandyopadhyay","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satyaki","family":"Manna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrija","family":"Hajra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanima Das","family":"Bhattacharya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2015,11,12]]},"reference":[{"key":"2025042707363018000_2015.nov12_1.bcr2015212821.1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1996.396933.x"},{"key":"2025042707363018000_2015.nov12_1.bcr2015212821.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1994.tb06734.x"},{"key":"2025042707363018000_2015.nov12_1.bcr2015212821.3","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-02-553800"},{"key":"2025042707363018000_2015.nov12_1.bcr2015212821.4","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2404955"},{"key":"2025042707363018000_2015.nov12_1.bcr2015212821.5","doi-asserted-by":"crossref","first-page":"2410","DOI":"10.1182\/blood.V88.7.2410.bloodjournal8872410","article-title":"Neutrophilic chronic myeloid leukemia: a distinct disease with a specific molecular marker (BCR\/ABL with C3\/A2 junction)","volume":"88","author":"Pane","year":"1996","journal-title":"Blood"},{"key":"2025042707363018000_2015.nov12_1.bcr2015212821.6","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2210"},{"key":"2025042707363018000_2015.nov12_1.bcr2015212821.7","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8588(03)00080-7"},{"key":"2025042707363018000_2015.nov12_1.bcr2015212821.8","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)71142-9"},{"key":"2025042707363018000_2015.nov12_1.bcr2015212821.9","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2401993"},{"key":"2025042707363018000_2015.nov12_1.bcr2015212821.10","first-page":"95","article-title":"Morphology and classification of the myelodysplastic syndromes and their pathologic variants","volume":"33","author":"Kouides","year":"1996","journal-title":"Semin Hematol"},{"key":"2025042707363018000_2015.nov12_1.bcr2015212821.11","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1182\/blood.V90.2.479","article-title":"Juvenile myelomonocytic leukemia","volume":"90","author":"Arico","year":"1997","journal-title":"Blood"},{"key":"2025042707363018000_2015.nov12_1.bcr2015212821.12","unstructured":"Vardiman JW , Bain BJ , Brunning RD , Thiele J . Atypical chronic myeloid leukaemia, BCR-ABL1 negative. In: Swerdlow SHCE , Lee Harris N , et al . eds. WHO classification of tumors of haematopoietic and lymphoid tissues. Lyon, France: IARC Press, 2008:80\u20131."},{"key":"2025042707363018000_2015.nov12_1.bcr2015212821.13","unstructured":"Parikh M , Geibel J . Splenic infarct. Emedicine, 2014."}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2015-212821","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T14:36:38Z","timestamp":1745764598000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2015-212821"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,12]]},"references-count":13,"alternative-id":["10.1136\/bcr-2015-212821"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2015-212821","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2015,11,12]]}}}