{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T04:01:15Z","timestamp":1745812875868,"version":"3.40.4"},"reference-count":14,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2016,1,6]]},"abstract":"<jats:p>A 62-year-old man presented to his general practitioner with a 10-day history of dark red urine. Subsequent blood tests revealed an acute kidney injury and anaemia. His only medical history was a prosthetic mitral valve replacement 30\u2005years previously for rheumatic valve disease. Following referral to a urology service, initial investigations, including CT KUB (kidneys, ureters, bladder), excluded a urological cause for his presentation. A haemolysis screen was positive. A transthoracic echocardiogram reported severe aortic stenosis and aortic incompetence. A transoesophageal echocardiogram revealed a paravalvular leak at the prosthetic mitral valve. The patient was referred to a regional cardiothoracic centre, and underwent a repeat mitral valve replacement and an aortic valve replacement.<\/jats:p>","DOI":"10.1136\/bcr-2015-213399","type":"journal-article","created":{"date-parts":[[2016,2,15]],"date-time":"2016-02-15T02:09:17Z","timestamp":1455502157000},"page":"bcr2015213399","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["A man with dark urine and shortness of breath: a case-based review of paravalvular leaks"],"prefix":"10.1136","volume":"2016","author":[{"given":"James P","family":"Curtain","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James William","family":"O'Brien","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2016,1,20]]},"reference":[{"key":"2025042702315098000_2016.jan20_1.bcr2015213399.1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2010.03.025"},{"key":"2025042702315098000_2016.jan20_1.bcr2015213399.2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs347"},{"key":"2025042702315098000_2016.jan20_1.bcr2015213399.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.03.074"},{"key":"2025042702315098000_2016.jan20_1.bcr2015213399.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2013.10.009"},{"key":"2025042702315098000_2016.jan20_1.bcr2015213399.5","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/suq009"},{"key":"2025042702315098000_2016.jan20_1.bcr2015213399.6","first-page":"431","article-title":"Erythropoietin can obviate the need for repeated heart valve replacement in high-risk patients with severe mechanical hemolytic anemia: case reports and literature review","volume":"10","author":"Shapira","year":"2001","journal-title":"J Heart Valve Dis"},{"key":"2025042702315098000_2016.jan20_1.bcr2015213399.7","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.110.960955"},{"key":"2025042702315098000_2016.jan20_1.bcr2015213399.8","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs109"},{"key":"2025042702315098000_2016.jan20_1.bcr2015213399.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2010.08.042"},{"key":"2025042702315098000_2016.jan20_1.bcr2015213399.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2004.02.014"},{"key":"2025042702315098000_2016.jan20_1.bcr2015213399.11","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00834-2"},{"key":"2025042702315098000_2016.jan20_1.bcr2015213399.12","doi-asserted-by":"publisher","DOI":"10.1136\/heart.89.11.1316"},{"key":"2025042702315098000_2016.jan20_1.bcr2015213399.13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.12.060"},{"key":"2025042702315098000_2016.jan20_1.bcr2015213399.14","first-page":"426","article-title":"Does the morphology of mitral paravalvular leaks influence symptoms and hemolysis?","volume":"10","author":"Genoni","year":"2001","journal-title":"J Heart Valve Dis"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2015-213399","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T09:31:56Z","timestamp":1745746316000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2015-213399"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1,20]]},"references-count":14,"alternative-id":["10.1136\/bcr-2015-213399"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2015-213399","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2016,1,20]]}}}