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Arriving at the emergency department, she had dyspnoea due to increasingly severe angio-oedema of the upper airways. Neither adrenaline inhalations, intravenously administrated corticosteroids, atropine nor furosemide were effective and the patient soon become bradycardic. A tracheotomy was performed and the patient was placed on a ventilator. She eventually made a full recovery. It was concluded that she had suffered from life-threatening angio-oedema due to her new medication.<\/jats:p>","DOI":"10.1136\/bcr-2016-214364","type":"journal-article","created":{"date-parts":[[2016,5,26]],"date-time":"2016-05-26T11:18:32Z","timestamp":1464261512000},"page":"bcr2016214364","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Life-threatening angio-oedema after the first dose of an ACE inhibitor\u2014not an anaphylactic reaction"],"prefix":"10.1136","volume":"2016","clinical-trial-number":[{"clinical-trial-number":"nct01843530","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Troels","family":"Krogh Nielsen","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, University Hospital of Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anette","family":"Bygum","sequence":"additional","affiliation":[{"name":"Dermatology and Allergy Center, University Hospital of Odense, Odense, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Rye Rasmussen","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, University Hospital of Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2016,5,26]]},"reference":[{"key":"2025082707260139000_2016.may26_1.bcr2016214364.1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12380"},{"key":"2025082707260139000_2016.may26_1.bcr2016214364.2","first-page":"244","article-title":"Life-threatening angio-oedema and death associated with the ACE inhibitor enalapril","volume":"97","author":"Cupido","year":"2007","journal-title":"S Afr Med J"},{"key":"2025082707260139000_2016.may26_1.bcr2016214364.3","doi-asserted-by":"publisher","DOI":"10.1177\/000348941011901208"},{"key":"2025082707260139000_2016.may26_1.bcr2016214364.4","doi-asserted-by":"publisher","DOI":"10.1097\/FPC.0b013e328363c137"},{"key":"2025082707260139000_2016.may26_1.bcr2016214364.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.iac.2006.08.001"},{"key":"2025082707260139000_2016.may26_1.bcr2016214364.6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1312524"},{"key":"2025082707260139000_2016.may26_1.bcr2016214364.7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2005.00819.x"},{"key":"2025082707260139000_2016.may26_1.bcr2016214364.8","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25113"},{"key":"2025082707260139000_2016.may26_1.bcr2016214364.9","doi-asserted-by":"publisher","DOI":"10.1177\/0897190012465990"},{"key":"2025082707260139000_2016.may26_1.bcr2016214364.10","doi-asserted-by":"publisher","DOI":"10.1177\/0003489414543069"},{"key":"2025082707260139000_2016.may26_1.bcr2016214364.11","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.5.5.643"},{"key":"2025082707260139000_2016.may26_1.bcr2016214364.12","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1760"},{"key":"2025082707260139000_2016.may26_1.bcr2016214364.13","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0546(08)72537-0"},{"key":"2025082707260139000_2016.may26_1.bcr2016214364.14","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)09137-X"},{"key":"2025082707260139000_2016.may26_1.bcr2016214364.15","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.107.096552"},{"key":"2025082707260139000_2016.may26_1.bcr2016214364.16","doi-asserted-by":"publisher","DOI":"10.1097\/FPC.0b013e32833d3acb"},{"key":"2025082707260139000_2016.may26_1.bcr2016214364.17","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2014.07.014"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2016-214364","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:26:08Z","timestamp":1756304768000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2016-214364"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,26]]},"references-count":17,"alternative-id":["10.1136\/bcr-2016-214364"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2016-214364","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2016,5,26]]}}}