{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T11:10:10Z","timestamp":1745752210175,"version":"3.40.4"},"reference-count":8,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2016,5,13]]},"abstract":"<jats:p>A 6\u00bd\u2005years Indian boy was brought by his parents, who were anxious about the excessive increase in the size of the boy's phallus, from the age of 2\u2005years. On physical examination, the child had a penis length greater than the 97th centile for age, a sexual maturity rating of gonads at stage 2 and pubic hair at stage 3, with height in the high normal range (90\u201397th centile). The bone age was 12\u2005years. Laboratory evaluation showed pubertal levels of testosterone and pubertal gonadotropin response to stimulation, confirming central precocious puberty (CPP). Incidentally, the hormonal profile also suggested congenital adrenal hyperplasia (CAH). This case report depicts a case of CPP probably caused by CAH in boys, which is rare.<\/jats:p>","DOI":"10.1136\/bcr-2016-214554","type":"journal-article","created":{"date-parts":[[2016,6,2]],"date-time":"2016-06-02T08:55:02Z","timestamp":1464857702000},"page":"bcr2016214554","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Boy with central precocious puberty probably due to a peripheral cause"],"prefix":"10.1136","volume":"2016","author":[{"given":"Pranab Kumar","family":"Sahana","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6589-0487","authenticated-orcid":false,"given":"Krishna Shankar","family":"Gopal Sankar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nilanjan","family":"Sengupta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaustubh","family":"Chattopadhyay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2016,6,2]]},"reference":[{"key":"2025042703293079000_2016.jun02_1.bcr2016214554.1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-58-5-857"},{"key":"2025042703293079000_2016.jun02_1.bcr2016214554.2","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/S0026-0495(97)90186-4","article-title":"Congenital adrenal hyperplasia complicated by central precocious puberty: linear growth during infancy and treatment with gonadotropin-releasing hormone analog","volume":"6","author":"Soliman","year":"1997","journal-title":"Metabolism"},{"key":"2025042703293079000_2016.jun02_1.bcr2016214554.3","doi-asserted-by":"publisher","DOI":"10.1007\/s13312-015-0566-5"},{"key":"2025042703293079000_2016.jun02_1.bcr2016214554.4","doi-asserted-by":"publisher","DOI":"10.1136\/adc.44.235.291"},{"key":"2025042703293079000_2016.jun02_1.bcr2016214554.5","first-page":"156","article-title":"Micropenis. I. Criteria, etiologies and classification","volume":"146","author":"Lee","year":"1980","journal-title":"Johns Hopkins Med J"},{"key":"2025042703293079000_2016.jun02_1.bcr2016214554.6","unstructured":"Grumbach MM . True or central precocious puberty. In: Kreiger DT , Bardin CW , eds. Current therapy in endocrinology and metabolism. Toronto, BC: Decker, 1985:4\u20138."},{"key":"2025042703293079000_2016.jun02_1.bcr2016214554.7","unstructured":"Melmed S , Polonsky SK , Larsen RP , et al . Flow chart for diagnosing sexual precocity in a phenotypic male. Figure\u00a025-72. In: Melmed S , Polonsky SK , Larsen R , et al . eds. WILLIAMS textbook of endocrinology. 12th edn. Elsevier Saunders, 2012:25\u201372."},{"key":"2025042703293079000_2016.jun02_1.bcr2016214554.8","unstructured":"Melmed S , Polonsky SK , Larsen RP , et al . Differential diagnosis of sexual precocity. Table\u00a025-4. In: Melmed S , Polonsky SK , Larsen R , et al . eds. WILLIAMS textbook of endocrinology. 12th edn. Elsevier Saunders, 2012:1175."}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2016-214554","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T10:29:41Z","timestamp":1745749781000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2016-214554"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,2]]},"references-count":8,"alternative-id":["10.1136\/bcr-2016-214554"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2016-214554","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2016,6,2]]}}}