{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T22:55:21Z","timestamp":1785797721206,"version":"3.56.0"},"reference-count":11,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2016,3,21]]},"abstract":"<jats:p>Medication-related osteonecrosis of the jaw (MRONJ) is a complication in patients who are on anti-bone resorptive drugs. These drugs are prescribed for patients with multiple myeloma, osteoporosis, metastatic carcinoma and Paget's disease. Common anti-bone resorptive drugs such as bisphosphonate and monoclonal antibodies such as denosumab are prescribed for these patients to prevent bone resorption. Although very effective in preventing bone resorption, a complication arising from these groups of drugs is the development of osteomyelitis of the jaw. This medication-related osteonecrosis occurs only in the jaw bones. It could mimic a metastatic jaw tumour when a patient reports to the dental surgeon with pain and swelling in the jaw. This case report describes MRONJ in a 50-year-old Indian woman. This possible painful drug-induced complication of jaw bones can be prevented if proper medical history is taken and management protocol is followed in these patients.<\/jats:p>","DOI":"10.1136\/bcr-2016-214626","type":"journal-article","created":{"date-parts":[[2016,4,6]],"date-time":"2016-04-06T16:54:43Z","timestamp":1459961683000},"page":"bcr2016214626","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":11,"title":["Medication-related osteonecrosis of the jaw: a dentist's nightmare"],"prefix":"10.1136","volume":"2016","author":[{"given":"Arvind","family":"Muthukrishnan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laliytha","family":"Bijai Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gomathi","family":"Ramalingam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2016,4,6]]},"reference":[{"key":"2025042703075470000_2016.apr06_1.bcr2016214626.1","doi-asserted-by":"crossref","first-page":"672","DOI":"10.12968\/denu.2011.38.10.672","article-title":"A current update on osteonecrosis of the jaw and bisphosphonates","volume":"38","author":"Arrain","year":"2011","journal-title":"Dent Update"},{"key":"2025042703075470000_2016.apr06_1.bcr2016214626.2","doi-asserted-by":"crossref","unstructured":"Ruggiero SL , Dobson TB , Fantasia J , et al . 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Osteomyelitis of jaws. 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