{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:16:46Z","timestamp":1756383406549,"version":"3.44.0"},"reference-count":6,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2016,7,27]]},"abstract":"<jats:p>There are \u223c250 cases of neonatal bacterial meningitis each year in the UK. Clinical evaluation of signs and symptoms of meningitis is challenging, particularly, during the neonatal period. Although uncommon, it is recognised that bacterial meningitis can be present in a child with an apparently normal cerebrospinal fluid (CSF) initially.We report the case of a newborn baby girl who was admitted with concerns regarding 2 dusky episodes. She underwent blood tests, a lumbar puncture and was started on intravenous antibiotics. With negative cultures, normal blood results and following a significant clinical improvement, antibiotics were discontinued after 48\u2005hours and the baby was discharged home. She re-presented to the children's emergency department 7\u2005hours later with a history of an apnoeic episode. A second CSF sample was suggestive of bacterial meningitis. We will discuss the published literature and the potential drawbacks of lumbar punctures and ways to diagnose meningitis early.<\/jats:p>","DOI":"10.1136\/bcr-2016-214636","type":"journal-article","created":{"date-parts":[[2016,8,11]],"date-time":"2016-08-11T10:32:47Z","timestamp":1470911567000},"page":"bcr2016214636","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Recognising early meningitis: a missed opportunity to diagnose meningitis"],"prefix":"10.1136","volume":"2016","author":[{"given":"Anusha","family":"Ponnampalam","sequence":"first","affiliation":[{"name":"Nottingham University Hospitals NHS Trust, Nottingham Children's Hospital, Nottingham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula","family":"de Sousa","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Conquest Hospital, Saint Leonards on Sea, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Will","family":"Carroll","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Royal Stoke University Hospital, Stoke-on-Trent, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2016,8,11]]},"reference":[{"key":"2025082804323994000_2016.aug11_1.bcr2016214636.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2011.02.038"},{"key":"2025082804323994000_2016.aug11_1.bcr2016214636.2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.53.7.590"},{"key":"2025082804323994000_2016.aug11_1.bcr2016214636.3","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-1132"},{"key":"2025082804323994000_2016.aug11_1.bcr2016214636.4","doi-asserted-by":"publisher","DOI":"10.1172\/JCI104485"},{"key":"2025082804323994000_2016.aug11_1.bcr2016214636.5","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1975.02120420038014"},{"key":"2025082804323994000_2016.aug11_1.bcr2016214636.6","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1093\/clinchem\/27.8.1431","article-title":"Early (chemical) diagnosis of bacterial meningitis\u2014cerebrospinal fluid glucose, lactate, and lacate dehydrogenase compared","volume":"27","author":"Knight","year":"1981","journal-title":"Clin Chem"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2016-214636","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:32:47Z","timestamp":1756380767000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2016-214636"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,11]]},"references-count":6,"alternative-id":["10.1136\/bcr-2016-214636"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2016-214636","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2016,8,11]]}}}