{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T21:15:16Z","timestamp":1776114916396,"version":"3.50.1"},"reference-count":20,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2016,4,20]]},"abstract":"<jats:p>We present a case of a 40-year-old man with decompensated alcoholic liver cirrhosis presenting with atraumatic cellulitis of one extremity and severe sepsis that rapidly progressed to compartment syndrome despite broad-spectrum antibiotics. Local cultures following debridement revealed<jats:italic>Vibrio vulnificus<\/jats:italic>, and subsequent history revealed consumption of raw oysters 48\u2005h before presentation. Our case points out the unique susceptibility of those with cirrhosis and elevated iron saturation to<jats:italic>Vibrio<\/jats:italic>septicaemia, as well as the rapidity and severity of the disease progression.<\/jats:p>","DOI":"10.1136\/bcr-2016-214772","type":"journal-article","created":{"date-parts":[[2016,5,5]],"date-time":"2016-05-05T13:28:09Z","timestamp":1462454889000},"page":"bcr2016214772","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":10,"title":["<i>Vibrio vulnificus<\/i>infection and liver cirrhosis: a potentially lethal combination"],"prefix":"10.1136","volume":"2016","author":[{"given":"Salik","family":"Nazir","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krysta","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann Kyungwohn","family":"Shin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony A","family":"Donato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2016,5,5]]},"reference":[{"key":"2025042703201954000_2016.may05_1.bcr2016214772.1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciq251"},{"key":"2025042703201954000_2016.may05_1.bcr2016214772.2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268805003894"},{"key":"2025042703201954000_2016.may05_1.bcr2016214772.3","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-109-4-318"},{"key":"2025042703201954000_2016.may05_1.bcr2016214772.4","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/173.5.1176"},{"key":"2025042703201954000_2016.may05_1.bcr2016214772.5","doi-asserted-by":"publisher","DOI":"10.1086\/515367"},{"key":"2025042703201954000_2016.may05_1.bcr2016214772.6","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01084-06"},{"key":"2025042703201954000_2016.may05_1.bcr2016214772.7","first-page":"1399","article-title":"The virulence of Vibrio vulnificus is affected by the cellular level of superoxide dismutase activity","volume":"17","author":"Kang","year":"2007","journal-title":"J Microbiol Biotechnol"},{"key":"2025042703201954000_2016.may05_1.bcr2016214772.8","doi-asserted-by":"publisher","DOI":"10.1128\/JB.187.17.5984-5995.2005"},{"key":"2025042703201954000_2016.may05_1.bcr2016214772.9","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.7.4212-4216.2003"},{"key":"2025042703201954000_2016.may05_1.bcr2016214772.10","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199604000-00012"},{"key":"2025042703201954000_2016.may05_1.bcr2016214772.11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01286.x"},{"key":"2025042703201954000_2016.may05_1.bcr2016214772.12","doi-asserted-by":"publisher","DOI":"10.1086\/314554"},{"key":"2025042703201954000_2016.may05_1.bcr2016214772.13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2005.40814.x"},{"key":"2025042703201954000_2016.may05_1.bcr2016214772.14","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.45861-0"},{"key":"2025042703201954000_2016.may05_1.bcr2016214772.15","unstructured":"Vibrio Illness [Internet]. Center for Disease Control and Prevention. http:\/\/www.cdc.gov\/vibrio\/vibriov.html (accessed 21 Dec 2015)."},{"key":"2025042703201954000_2016.may05_1.bcr2016214772.16","unstructured":"National Center for Emerging and Zoonotic Infectious Diseases, Division of Foodborne, Waterborne, and Environmental Diseases. National Enteric Disease Surveillance: COVIS Annual Summary, 2013. 2015. http:\/\/www.cdc.gov\/ncezid\/dfwed\/pdfs\/covis-annual-report-2013-508c.pdf"},{"key":"2025042703201954000_2016.may05_1.bcr2016214772.17","first-page":"539","article-title":"Vibrio vulnificus infection: diagnosis and treatment","volume":"76","author":"Bross","year":"2007","journal-title":"Am Fam Physician"},{"key":"2025042703201954000_2016.may05_1.bcr2016214772.18","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0691.2003.00680.x"},{"key":"2025042703201954000_2016.may05_1.bcr2016214772.19","doi-asserted-by":"crossref","unstructured":"Emamifar A , Asmussen Andreasen R , Skaarup Andersen N , et al . Septic arthritis and subsequent fatal septic shock caused by Vibrio vulnificus infection. BMJ Case Rep 2015;2015. doi:10.1136\/bcr-2015-212014","DOI":"10.1136\/bcr-2015-212014"},{"key":"2025042703201954000_2016.may05_1.bcr2016214772.20","first-page":"405","article-title":"Vibrio vulnificus infections associated with raw oyster consumption\u2014Florida, 1981-1992","volume":"42","author":"Centers for Disease Control and Prevention (CDC)","year":"1993","journal-title":"MMWR Morb Mortal Wkly Rep"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2016-214772","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T10:20:29Z","timestamp":1745749229000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2016-214772"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,5]]},"references-count":20,"alternative-id":["10.1136\/bcr-2016-214772"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2016-214772","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,5]]}}}