{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:02:22Z","timestamp":1756339342018,"version":"3.44.0"},"reference-count":8,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2017,1,14]]},"abstract":"<jats:p>A man aged 51 years presented with sudden onset, horizontal, binocular, double vision and right facial weakness. Ocular motility examination demonstrated a right horizontal gaze palsy pattern in keeping with a one-and-a-half syndrome. Since this was associated with a concomitant, ipsilateral, lower motor neuron (LMN) facial (VIIth) cranial nerve palsy, he had acquired an eight-and-a-half syndrome. Diffusion-weighted MRI confirmed a small infarcted area in the pons of the brainstem which correlated with anatomical location of the horizontal gaze centre and VIIth cranial nerve fasciculus. As a result of this presentation, further investigations uncovered a hitherto undiagnosed blood dyscrasia\u2014namely polycythaemia vera. Regular venesection was started which resulted in complete resolution of his ocular motility dysfunction and an improvement of his LMN facial nerve palsy.<\/jats:p>","DOI":"10.1136\/bcr-2016-214955","type":"journal-article","created":{"date-parts":[[2017,1,30]],"date-time":"2017-01-30T10:30:29Z","timestamp":1485772229000},"page":"bcr2016214955","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Blood, brain and binocular vision"],"prefix":"10.1136","volume":"2017","author":[{"given":"Egle","family":"Rostron","sequence":"first","affiliation":[{"name":"Ophthalmology Department, St James Hospital, Leeds, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary Polly","family":"Dickerson","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, St James Hospital, Leeds, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory","family":"Heath","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, York Teaching Hospital, York, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,1,30]]},"reference":[{"key":"2025082623272183000_2017.jan30_1.bcr2016214955.1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2007.06741.x"},{"key":"2025082623272183000_2017.jan30_1.bcr2016214955.2","unstructured":"Polycythaemia\/erythrocytosis. NICE Clinical Guideline (July 2010). http:\/\/www.nice.org.uk\/guidance\/"},{"key":"2025082623272183000_2017.jan30_1.bcr2016214955.3","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.61.6474"},{"key":"2025082623272183000_2017.jan30_1.bcr2016214955.4","doi-asserted-by":"crossref","first-page":"230","DOI":"10.5492\/wjccm.v4.i3.230","article-title":"Myeloproliferative and thrombotic burden and treatment outcome of thrombocythemia and polycythemia patients","volume":"4","author":"Michiels","year":"2015","journal-title":"World J Crit Care Med"},{"key":"2025082623272183000_2017.jan30_1.bcr2016214955.5","unstructured":"Weakness of the facial muscles. In: Nerad J , ed. Techniques in ophthalmic plastic surgery. London: Elsevier, 2010;244\u201360."},{"key":"2025082623272183000_2017.jan30_1.bcr2016214955.6","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.jstrokecerebrovasdis.2014.01.002","article-title":"Eight-and-a-half syndrome: a rare presentation of pontine infarction","volume":"23","author":"Sampath Kumar","year":"2014","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"2025082623272183000_2017.jan30_1.bcr2016214955.7","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1097\/00041327-199806000-00008","article-title":"Eight-and-a-half syndrome: one-and-a-half syndrome plus cranial nerve VII palsy","volume":"18","author":"Eggenberger","year":"1998","journal-title":"J Neuroophthal"},{"key":"2025082623272183000_2017.jan30_1.bcr2016214955.8","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.33.8.971"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2016-214955","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T06:27:32Z","timestamp":1756276052000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2016-214955"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,30]]},"references-count":8,"alternative-id":["10.1136\/bcr-2016-214955"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2016-214955","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2017,1,30]]}}}