{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T10:15:05Z","timestamp":1776334505446,"version":"3.51.2"},"reference-count":14,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2016,10,25]]},"abstract":"<jats:p>Hereditary haemochromatosis is associated with increased susceptibility to some infections. We report here a case of Q fever in a patient with coexistent haemochromatosis. The literature is reviewed in regard to the effect of haemochromatosis on susceptibility to infectious disease in general and Q fever in particular. Although there is documented increased risk in these patients for some infectious conditions, a specific association with Q fever has not been previously reported. The present report raises the possibility of such a clinically relevant connection.<\/jats:p>","DOI":"10.1136\/bcr-2016-215214","type":"journal-article","created":{"date-parts":[[2016,11,9]],"date-time":"2016-11-09T08:57:53Z","timestamp":1478681873000},"page":"bcr2016215214","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Q fever hepatitis and endocarditis in the context of haemochromatosis"],"prefix":"10.1136","volume":"2016","author":[{"given":"Hesham","family":"Elgouhari","sequence":"first","affiliation":[{"name":"Avera Medical Group Liver Disease, Sioux Falls, South Dakota, USA"},{"name":"Department of Internal Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6009-0464","authenticated-orcid":false,"given":"Mark K","family":"Huntington","sequence":"additional","affiliation":[{"name":"Center for Family Medicine, Sioux Falls, South Dakota, USA"},{"name":"Department of Family Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2016,11,9]]},"reference":[{"key":"2025082802404281000_2016.nov08_2.bcr2016215214.1","doi-asserted-by":"publisher","DOI":"10.1080\/01652176.2013.843809"},{"key":"2025082802404281000_2016.nov08_2.bcr2016215214.2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(92)90173-9"},{"key":"2025082802404281000_2016.nov08_2.bcr2016215214.3","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02365-05"},{"key":"2025082802404281000_2016.nov08_2.bcr2016215214.4","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.nutr.26.061505.111226"},{"key":"2025082802404281000_2016.nov08_2.bcr2016215214.5","doi-asserted-by":"publisher","DOI":"10.1038\/ng0896-399"},{"key":"2025082802404281000_2016.nov08_2.bcr2016215214.6","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1093\/jn\/137.5.1341","article-title":"Host\u2013pathogen interactions: the role of iron","volume":"137","author":"Doherty","year":"2007","journal-title":"J Nutr"},{"key":"2025082802404281000_2016.nov08_2.bcr2016215214.7","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1991.00400080096018"},{"key":"2025082802404281000_2016.nov08_2.bcr2016215214.8","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1182\/blood.V79.7.1855.1855","article-title":"Decreased concentrations of tumor necrosis factor-alpha in supernatants of monocytes from homozygotes for hereditary hemochromatosis","volume":"79","author":"Gordeuk","year":"1992","journal-title":"Blood"},{"key":"2025082802404281000_2016.nov08_2.bcr2016215214.9","doi-asserted-by":"crossref","first-page":"2259","DOI":"10.4049\/jimmunol.162.4.2259","article-title":"IFN-gamma-mediated control of Coxiella burnetii survival in monocytes: the role of cell apoptosis and TNF","volume":"162","author":"Dellacasagrande","year":"1999","journal-title":"J Immunol"},{"key":"2025082802404281000_2016.nov08_2.bcr2016215214.10","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.1.160-164.2000"},{"key":"2025082802404281000_2016.nov08_2.bcr2016215214.11","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01767-06"},{"key":"2025082802404281000_2016.nov08_2.bcr2016215214.12","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2014-205455"},{"key":"2025082802404281000_2016.nov08_2.bcr2016215214.13","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.181.4.2723"},{"key":"2025082802404281000_2016.nov08_2.bcr2016215214.14","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0039363"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2016-215214","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:40:47Z","timestamp":1756374047000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2016-215214"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,9]]},"references-count":14,"alternative-id":["10.1136\/bcr-2016-215214"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2016-215214","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,9]]}}}