{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T20:42:51Z","timestamp":1782420171651,"version":"3.54.5"},"reference-count":9,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2016,4,25]]},"abstract":"<jats:p>A 50-year-old man was admitted in midwinter with fever, altered mental status and new onset generalised tonic-clonic seizure with urinary incontinence. Cerebrospinal fluid (CSF) analysis revealed an opening pressure of 14.5\u2005cm of water, normal glucose and protein 82\u2005mg\/dL (reference range: 15\u201345\u2005mg\/dL). Cell count showed: red cells 11 (reference range: &lt;5\u2005mm<jats:sup>3<\/jats:sup>), white cell count 1 (reference range: &lt;5\u2005mm<jats:sup>3<\/jats:sup>). The patient's blood and CSF cultures had no growth. MRI of the brain with and without gadolinium contrast showed abnormal T2 and fluid-attenuated inversion recovery signals within bilateral ventricular nuclei, hippocampi, left frontal and parietal regions. Eastern equine encephalitis (EEE) antibody, IgG titre was 1:64 and IgM titre was &lt;1:16. Three weeks later, his repeat\/convalescent titres increased to 1:1024 and 1:32, respectively. Hence, a diagnosis of EEE was established. The patient was treated with supportive care. He recovered well with mildly impaired memory but no other cognitive deficits.<\/jats:p>","DOI":"10.1136\/bcr-2016-215270","type":"journal-article","created":{"date-parts":[[2016,5,10]],"date-time":"2016-05-10T12:11:18Z","timestamp":1462882278000},"page":"bcr2016215270","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Case of eastern equine encephalitis presenting in winter"],"prefix":"10.1136","volume":"2016","author":[{"given":"Kairav J","family":"Shah","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Infectious Diseases, University of Florida, Gainesville, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kartikeya","family":"Cherabuddi","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Infectious Diseases, University of Florida, Gainesville, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2016,5,10]]},"reference":[{"key":"2025082722533892000_2016.may10_1.bcr2016215270.1","unstructured":"CDC. 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