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She was initially treated with intrathecal methotrexate, which was stopped due to toxicity, followed by maintenance endocrine therapy. She achieved a sustained complete radiological and cerebrospinal fluid cytological response for over 9\u2005years. She eventually passed away of ischaemic bowel unrelated to her cancer.<\/jats:p>","DOI":"10.1136\/bcr-2016-215525","type":"journal-article","created":{"date-parts":[[2016,6,2]],"date-time":"2016-06-02T04:55:02Z","timestamp":1464843302000},"page":"bcr2016215525","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Complete response and long-term survival of leptomeningeal carcinomatosis from breast cancer with maintenance endocrine therapy"],"prefix":"10.1136","volume":"2016","author":[{"given":"Muneera Majed","family":"Almajed","sequence":"first","affiliation":[{"name":"Jewish General Hospital, McGill University, Montreal, Quebec, Canada"},{"name":"Oncology Department, Prince Sultan Military Medical City, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khashayar","family":"Esfahani","sequence":"additional","affiliation":[{"name":"Jewish General Hospital, McGill University, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Pelmus","sequence":"additional","affiliation":[{"name":"Pathology Department, Jewish General Hospital, McGill University, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence","family":"Panasci","sequence":"additional","affiliation":[{"name":"Jewish General Hospital, McGill University, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2016,6,2]]},"reference":[{"key":"2025082704065433000_2016.jun02_1.bcr2016215525.1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-015-2042-y"},{"key":"2025082704065433000_2016.jun02_1.bcr2016215525.2","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-013-1092-8"},{"key":"2025082704065433000_2016.jun02_1.bcr2016215525.3","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-008-0645-y"},{"key":"2025082704065433000_2016.jun02_1.bcr2016215525.4","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1991.147"},{"key":"2025082704065433000_2016.jun02_1.bcr2016215525.5","first-page":"75","article-title":"Carcinomatous meningitis secondary to breast cancer. 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