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We present a case of acute pericarditis evolving in pericardial constriction and cardiac tamponade in a patient treated with adalimumab for psoriatic arthritis overlapping with recurrent polychondritis. Next-generation sequencing allowed the identification of a common oral pathogen as the aetiological agent confirming its role in the identification of species that can be overlooked by common microbiological techniques.<\/jats:p>","DOI":"10.1136\/bcr-2016-215529","type":"journal-article","created":{"date-parts":[[2016,8,29]],"date-time":"2016-08-29T15:48:04Z","timestamp":1472485684000},"page":"bcr2016215529","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Molecular diagnosis of opportunistic pericardial infection in a patient treated with adalimumab: the role of next-generation sequencing"],"prefix":"10.1136","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4987-262X","authenticated-orcid":false,"given":"Stefano","family":"Poli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manola","family":"Comar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Luzzati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianfranco","family":"Sinagra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2016,8,29]]},"reference":[{"key":"2025042703562744000_2016.aug29_1.bcr2016215529.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2009.08.006"},{"key":"2025042703562744000_2016.aug29_1.bcr2016215529.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2006.08.010"},{"key":"2025042703562744000_2016.aug29_1.bcr2016215529.3","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.089276"},{"key":"2025042703562744000_2016.aug29_1.bcr2016215529.4","doi-asserted-by":"publisher","DOI":"10.2165\/00129784-200505020-00004"},{"key":"2025042703562744000_2016.aug29_1.bcr2016215529.5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1401268"},{"key":"2025042703562744000_2016.aug29_1.bcr2016215529.6","first-page":"53","article-title":"Purulent pericardial effusions with pericardial tamponade\u2014diagnosis and treatment issues","volume":"39","author":"Petcu","year":"2013","journal-title":"Curr Health Sci J"},{"key":"2025042703562744000_2016.aug29_1.bcr2016215529.7","doi-asserted-by":"publisher","DOI":"10.1002\/art.10529"},{"key":"2025042703562744000_2016.aug29_1.bcr2016215529.8","doi-asserted-by":"crossref","first-page":"pii: bcr0120125644","DOI":"10.1136\/bcr.01.2012.5644","article-title":"Complication of etanercept treatment for rheumatoid arthritis\u2014purulent pericarditis caused by a commensal organism","volume":"2012","author":"Taylor","year":"2012","journal-title":"BMJ Case Rep"},{"key":"2025042703562744000_2016.aug29_1.bcr2016215529.9","doi-asserted-by":"publisher","DOI":"10.2459\/JCM.0000000000000160"},{"key":"2025042703562744000_2016.aug29_1.bcr2016215529.10","first-page":"1090","article-title":"Periodontitis and porphyromonas gingivalis in patients with rheumatoid arthritis","volume":"66","author":"Mikuls","year":"2014","journal-title":"BMJ Case Rep"},{"key":"2025042703562744000_2016.aug29_1.bcr2016215529.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2015.06.017"},{"key":"2025042703562744000_2016.aug29_1.bcr2016215529.12","doi-asserted-by":"crossref","first-page":"5337","DOI":"10.1128\/IAI.66.11.5337-5343.1998","article-title":"Invasion of aortic and heart endothelial cells by porphyromonas gingivalis","volume":"66","author":"Deshpande","year":"1998","journal-title":"Infect Immun"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2016-215529","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T10:56:35Z","timestamp":1745751395000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2016-215529"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,29]]},"references-count":12,"alternative-id":["10.1136\/bcr-2016-215529"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2016-215529","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2016,8,29]]}}}