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During the most recent hospital admission, the patient was transferred to an innovative community-based clinical support residence that supported harm reduction. Initially, she received methadone to only manage the withdrawal symptoms rather than for long-term maintenance therapy. However, with gradual dose increases to treat cravings and withdrawal, she ultimately discontinued all drug use and reinitiated antiretroviral therapy. This case highlights that patients whose goal is not abstinence can be successfully treated for acute medical illnesses and comorbid substance use disorders using harm reduction approaches, including appropriate dosing of pharmacotherapy.<\/jats:p>","DOI":"10.1136\/bcr-2016-215557","type":"journal-article","created":{"date-parts":[[2016,7,12]],"date-time":"2016-07-12T16:40:29Z","timestamp":1468341629000},"page":"bcr2016215557","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Treatment of opioid use disorder in an innovative community-based setting after multiple treatment attempts in a woman with untreated HIV"],"prefix":"10.1136","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4766-4296","authenticated-orcid":false,"given":"Pauline","family":"Voon","sequence":"first","affiliation":[{"name":"Urban Health Research Initiative, BC Centre for Excellence in HIV\/AIDS, UBC, Vancouver, British Columbia, Canada"},{"name":"Faculty of Medicine, School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald","family":"Joe","sequence":"additional","affiliation":[{"name":"Department of Vancouver Community, Vancouver Coastal Health, Vancouver, British Columbia, Canada"},{"name":"Faculty of Medicine, Department of Family Medicine, University of British Columbia, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Fairgrieve","sequence":"additional","affiliation":[{"name":"Urban Health Research Initiative, BC Centre for Excellence in HIV\/AIDS, UBC, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keith","family":"Ahamad","sequence":"additional","affiliation":[{"name":"Urban Health Research Initiative, BC Centre for Excellence in HIV\/AIDS, UBC, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2016,7,11]]},"reference":[{"key":"2025082703195502000_2016.jul11_1.bcr2016215557.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)61462-6"},{"key":"2025082703195502000_2016.jul11_1.bcr2016215557.2","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2009.0242"},{"key":"2025082703195502000_2016.jul11_1.bcr2016215557.3","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2007.0092"},{"key":"2025082703195502000_2016.jul11_1.bcr2016215557.4","doi-asserted-by":"crossref","unstructured":"Mattick RP , Breen C , Kimber J , et al . 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