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Given her coagulopathy and absence of imminent haemodynamic compromise, pericardiocentesis was deferred. Unfortunately, 1\u2005day later, the patient deteriorated rapidly. By the time pericardiocentesis was performed and factor VIIa administered, the patient had already started developing multiple organ failure. She developed cardiac arrest and died 3\u2005days after her admission. Only 10 cases of hemopericardium attributable to warfarin have previously been reported. In this report, we review the literature and also describe how hyperthyroidism most likely predisposed our patient to bleeding complications from warfarin.<\/jats:p>","DOI":"10.1136\/bcr-2016-215731","type":"journal-article","created":{"date-parts":[[2016,7,14]],"date-time":"2016-07-14T00:42:20Z","timestamp":1468456940000},"page":"bcr2016215731","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Bleeding heart: a case of spontaneous hemopericardium and tamponade in a hyperthyroid patient on warfarin"],"prefix":"10.1136","volume":"2016","author":[{"given":"Muhammad","family":"Sajawal Ali","sequence":"first","affiliation":[{"name":"Department of Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin I","family":"Mba","sequence":"additional","affiliation":[{"name":"Department of Medicine, John H. 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