{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T10:10:10Z","timestamp":1756375810616,"version":"3.44.0"},"reference-count":8,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2016,5,3]]},"abstract":"<jats:p>We describe a rare case of a 75-year-old woman with significant non-steroidal anti-inflammatory drug (NSAID) use who presented with haematemesis. Upper endoscopy revealed a large (9\u2005cm) intramucosal dissection of the oesophagus without extension into the gastro-oesophageal junction and a severely narrowed pylorus. We postulate that she developed pyloric stenosis due to peptic ulcer disease from chronic NSAID use. This then led to gastro-oesophageal reflux. Undigested pills in the refluxate had contacted oesophageal mucosa, leading to pill-induced oesophageal injury. This, along with vomiting, is postulated to have led to the oesophageal intramucosal dissection. She improved with conservative medical management with a clear liquid diet and proton pump inhibitors, and a follow-up upper endoscopy 1\u2005week later showed recovery of the previously seen intramucosal dissection.<\/jats:p>","DOI":"10.1136\/bcr-2016-215777","type":"journal-article","created":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T15:44:16Z","timestamp":1716219856000},"page":"bcr2016215777","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["NSAID-induced pyloric stenosis leading to oesophageal intramucosal dissection"],"prefix":"10.1136","volume":"2016","author":[{"given":"Kai Rou","family":"Tey","sequence":"first","affiliation":[{"name":"Department of Medicine, University of Arizona College of Medicine, Tucson, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Kemmerly","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University of Arizona, Tucson, Arizona, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhaskar","family":"Banerjee","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University of Arizona, Tucson, Arizona, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2016,5,19]]},"reference":[{"key":"2025082802303473000_2016.may19_1.bcr2016215777.1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i31.10994"},{"key":"2025082802303473000_2016.may19_1.bcr2016215777.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2008.03187.x"},{"key":"2025082802303473000_2016.may19_1.bcr2016215777.3","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2013.71"},{"key":"2025082802303473000_2016.may19_1.bcr2016215777.4","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.36.422.743"},{"key":"2025082802303473000_2016.may19_1.bcr2016215777.5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2050.2009.00972.x"},{"key":"2025082802303473000_2016.may19_1.bcr2016215777.6","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1017\/S0022215108002582","article-title":"Oesophageal perforation following ingestion of over-the-counter ibuprofen capsules","volume":"122","author":"Singh","year":"2008","journal-title":"J Laryngol Otol"},{"key":"2025082802303473000_2016.may19_1.bcr2016215777.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2010.02.010"},{"key":"2025082802303473000_2016.may19_1.bcr2016215777.8","doi-asserted-by":"publisher","DOI":"10.1155\/DTE.4.149"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2016-215777","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:30:44Z","timestamp":1756373444000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2016-215777"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,19]]},"references-count":8,"alternative-id":["10.1136\/bcr-2016-215777"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2016-215777","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2016,5,19]]}}}