{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T22:44:02Z","timestamp":1777329842072,"version":"3.51.4"},"reference-count":5,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2016,9,19]]},"abstract":"<jats:p>A 24-year-old man with systemic lupus erythematosus and antiphospholipid syndrome complicated by lupus nephritis presented with acute limb ischaemia secondary to an embolus. Following embolectomy, the patient underwent a transthoracic echocardiogram which revealed a large vegetation on all three cusps of the aortic valve. The patient was taken for an urgent aortic valve replacement with a mechanical valve. Cultures of one cusp remained sterile. Histopathological examination of the remaining two cusps revealed sterile fibrin-rich thrombotic vegetations characteristic of non-bacterial thrombotic endocarditis.<\/jats:p>","DOI":"10.1136\/bcr-2016-215914","type":"journal-article","created":{"date-parts":[[2016,10,4]],"date-time":"2016-10-04T11:21:43Z","timestamp":1475580103000},"page":"bcr2016215914","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":11,"title":["Aortic valve replacement for Libman-Sacks endocarditis"],"prefix":"10.1136","volume":"2016","author":[{"given":"Jack B","family":"Keenan","sequence":"first","affiliation":[{"name":"Department of Surgery, University of Arizona College of Medicine, Tucson, Arizona, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajesh","family":"Janardhanan","sequence":"additional","affiliation":[{"name":"Sarver Heart Center, Tucson, Arizona, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon T","family":"Larsen","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Arizona Medical Center, Tucson, Arizona, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zain","family":"Khalpey","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University of Arizona, Tucson, Arizona, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2016,10,4]]},"reference":[{"key":"2025082702164735000_2016.oct04_1.bcr2016215914.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2003.07.016"},{"key":"2025082702164735000_2016.oct04_1.bcr2016215914.2","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.53.2232"},{"key":"2025082702164735000_2016.oct04_1.bcr2016215914.3","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1093\/oxfordjournals.eurheartj.a060367","article-title":"Rapid appearance of severe mitral regurgitation under high-dosage corticosteroid therapy in a patient with systemic lupus erythematosus","volume":"15","author":"Hoffman","year":"1994","journal-title":"Eur Heart J"},{"key":"2025082702164735000_2016.oct04_1.bcr2016215914.4","doi-asserted-by":"publisher","DOI":"10.1186\/1749-8090-5-13"},{"key":"2025082702164735000_2016.oct04_1.bcr2016215914.5","doi-asserted-by":"publisher","DOI":"10.1016\/S0894-7317(96)90112-1"}],"updated-by":[{"DOI":"10.1136\/bcr-2016-215914corr1","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2016,11,21]],"date-time":"2016-11-21T00:00:00Z","timestamp":1479686400000}}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2016-215914","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T09:16:53Z","timestamp":1756286213000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2016-215914"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,4]]},"references-count":5,"alternative-id":["10.1136\/bcr-2016-215914"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2016-215914","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,4]]}}}