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The patient underwent parathyroidectomy of the enlarged parathyroid gland. Final histopathology, however, revealed parathyroid carcinoma, 4.7\u2005cm in widest dimension, with capsular and vascular space invasion. The patient underwent repeat surgery, specifically, left thyroid lobectomy, isthmectomy and central node dissection. Intact PTH decreased from 681.3 to 74\u2005pg\/mL (normal range: 10\u201365) 24\u2005hours postoperatively. Follow-up at 6\u2005months showed normal serum calcium levels, size reduction of bone lesions and improvement of quality of life.<\/jats:p>","DOI":"10.1136\/bcr-2016-215961","type":"journal-article","created":{"date-parts":[[2016,6,29]],"date-time":"2016-06-29T17:28:24Z","timestamp":1467221304000},"page":"bcr2016215961","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Multiple brown tumours from parathyroid carcinoma"],"prefix":"10.1136","volume":"2016","author":[{"given":"Daryl Jade Tardo","family":"Dagang","sequence":"first","affiliation":[{"name":"Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, Philippine General Hospital, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerico Baliton","family":"Gutierrez","sequence":"additional","affiliation":[{"name":"Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, Philippine General Hospital, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark Anthony Santiago","family":"Sandoval","sequence":"additional","affiliation":[{"name":"Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, Philippine General Hospital, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frances Lina","family":"Lantion-Ang","sequence":"additional","affiliation":[{"name":"Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, Philippine General Hospital, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2016,6,29]]},"reference":[{"key":"2025082704113397000_2016.jun29_1.bcr2016215961.1","doi-asserted-by":"publisher","DOI":"10.4076\/1752-1947-3-7495"},{"key":"2025082704113397000_2016.jun29_1.bcr2016215961.2","doi-asserted-by":"crossref","unstructured":"Belizikian JP , Silverberg SJ . 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