{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T12:24:00Z","timestamp":1777465440169,"version":"3.51.4"},"reference-count":10,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2016,10,7]]},"abstract":"<jats:p>Sodium hypochlorite is a clear yellowish solution with a characteristic odour of chlorine and is commonly used as a disinfectant and a bleaching agent. It is used in various healthcare settings for its fast-acting and broad-spectrum antimicrobial activity. It is a known irritant and there are some reports that it can also cause allergic contact dermatitis of type IV hypersensitivity. We report a case of work-related type I hypersensitivity to sodium hypochlorite, presenting with recurrent urticarial rash and a positive prick test reaction to this chemical. He was subsequently excused from further exposure with no further recurrences of the urticarial rash. To the best of our knowledge, this is the first such reported case due to work in the healthcare setting.<\/jats:p>","DOI":"10.1136\/bcr-2016-217228","type":"journal-article","created":{"date-parts":[[2016,10,21]],"date-time":"2016-10-21T15:25:22Z","timestamp":1477063522000},"page":"bcr2016217228","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":22,"title":["Rare case of type I hypersensitivity reaction to sodium hypochlorite solution in a healthcare setting"],"prefix":"10.1136","volume":"2016","author":[{"given":"Gabriel","family":"Chia Shi Zhe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Green","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuke Tien","family":"Fong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haur Yueh","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sweet Far","family":"Ho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2016,10,21]]},"reference":[{"key":"2025042705332420000_2016.oct21_1.bcr2016217228.1","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1128\/CMR.10.4.597","article-title":"Uses of inorganic hypochlorite (bleach) in health-care facilities","volume":"10","author":"Rutala","year":"1997","journal-title":"Clin Microbiol Rev"},{"key":"2025042705332420000_2016.oct21_1.bcr2016217228.2","doi-asserted-by":"publisher","DOI":"10.1186\/2045-7022-3-3"},{"key":"2025042705332420000_2016.oct21_1.bcr2016217228.3","unstructured":"Agency for Toxic Substances and Disease Registry. Medical Management Guidelines for Calcium Hypochlorite. Secondary Medical Management Guidelines for Calcium Hypochlorite 21 October 2014. 2002."},{"key":"2025042705332420000_2016.oct21_1.bcr2016217228.4","unstructured":"Public Health England. Sodium hypochlorite toxicological overview. UK: Public Health England, 2015."},{"key":"2025042705332420000_2016.oct21_1.bcr2016217228.5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1986.tb01314.x"},{"key":"2025042705332420000_2016.oct21_1.bcr2016217228.6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1989.tb03218.x"},{"key":"2025042705332420000_2016.oct21_1.bcr2016217228.7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.1994.tb00247.x"},{"key":"2025042705332420000_2016.oct21_1.bcr2016217228.8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1977.tb03679.x"},{"key":"2025042705332420000_2016.oct21_1.bcr2016217228.9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1990.tb05165.x"},{"key":"2025042705332420000_2016.oct21_1.bcr2016217228.10","unstructured":"Public Health England. Sodium hypochlorite. General Information. PHE publications gateway number: 2014790. Published: October 2016."}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2016-217228","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T12:33:33Z","timestamp":1745757213000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2016-217228"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,21]]},"references-count":10,"alternative-id":["10.1136\/bcr-2016-217228"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2016-217228","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,21]]}}}