{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T12:21:18Z","timestamp":1764332478512,"version":"3.44.0"},"reference-count":7,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2017,1,12]]},"abstract":"<jats:p>Rumpel-Leede phenomenon (RLP), also known as acute capillary rupture syndrome (ACRS), is a rare occurrence where distal dermal capillaries rupture in response to a proximal compressive force, such as a blood pressure cuff or tourniquet. This phenomenon has been reported to occur in states of vascular fragility such as long-term steroid use, hypertension or diabetes mellitus. Here, we provide a report of RLP occurring secondary to tourniquet application in a 26-year-old woman with adult-onset Still's disease (AOSD) and a recent drug rash. In this case, the cause of the phenomenon is most likely multifactorial. Likely contributing factors include long-term steroid use for the treatment of AOSD, and increased vascular permeability secondary to the drug rash. Patients and clinicians should be aware that the treatment of AOSD may induce a state of capillary fragility and they should work together to minimise the risk of complications.<\/jats:p>","DOI":"10.1136\/bcr-2016-217290","type":"journal-article","created":{"date-parts":[[2017,1,27]],"date-time":"2017-01-27T09:30:33Z","timestamp":1485509433000},"page":"bcr2016217290","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Rumpel-Leede phenomenon in a patient with adult-onset Still's disease"],"prefix":"10.1136","volume":"2017","author":[{"given":"Jacob Trygve","family":"Lambdin","sequence":"first","affiliation":[{"name":"George Washington University School of Medicine and Health Sciences, Arlington, Virginia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Mackenzie","sequence":"additional","affiliation":[{"name":"George Washington University School of Medicine and Health Sciences, Stouffville, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,1,27]]},"reference":[{"key":"2025082700580526000_2017.jan27_1.bcr2016217290.1","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1213\/XAA.0000000000000309","article-title":"Rumpel-leede phenomenon in a patient with laboratory markers positive for Sjogren disease","volume":"6","author":"Ramme","year":"2016","journal-title":"A A Case Rep"},{"key":"2025082700580526000_2017.jan27_1.bcr2016217290.2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780250607"},{"key":"2025082700580526000_2017.jan27_1.bcr2016217290.3","first-page":"673","article-title":"Hepatic abnormalities in adult onset Still's disease","volume":"6","author":"Esdaile","year":"1979","journal-title":"J Rheumatol"},{"key":"2025082700580526000_2017.jan27_1.bcr2016217290.4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2009.07736.x"},{"key":"2025082700580526000_2017.jan27_1.bcr2016217290.5","first-page":"200","article-title":"Rumpel-Leede phenomenon presenting as a hypertensive urgency","volume":"29","author":"Varela","year":"2016","journal-title":"Proc (Bayl Univ Med Cent)"},{"key":"2025082700580526000_2017.jan27_1.bcr2016217290.6","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcv024"},{"key":"2025082700580526000_2017.jan27_1.bcr2016217290.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2006.12.010"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2016-217290","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T07:58:14Z","timestamp":1756281494000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2016-217290"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,27]]},"references-count":7,"alternative-id":["10.1136\/bcr-2016-217290"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2016-217290","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2017,1,27]]}}}