{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T15:41:28Z","timestamp":1759160488986,"version":"3.44.0"},"reference-count":6,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2017,2,10]]},"abstract":"<jats:p>Many diseases can cause hypercalcaemia, including primary hyperparathyroidism, cancer, drugs and granulomatous diseases. A nursing home resident aged 81 years was admitted because of altered mental status. The patient did not have fever, cough, sputum or night sweat. Hypercalcaemia was identified as a cause of the consciousness disturbance. Chest radiograph showed no acute process. Laboratory workups revealed elevated serum levels of 1,25-(OH)2 vitamin D<jats:sub>3<\/jats:sub> and positive T-spot test. Microscopic examination of the suctioned sputum identified acid-fast bacilli, which was confirmed as <jats:italic>Mycobactrium tuberculsosis<\/jats:italic>. Tuberculosis should be considered as the important cause of hypercalcaemia since early diagnosis and treatment is recommended for preventing its outbreak among people with close contacts with patients.<\/jats:p>","DOI":"10.1136\/bcr-2016-217797","type":"journal-article","created":{"date-parts":[[2017,2,25]],"date-time":"2017-02-25T00:55:17Z","timestamp":1487984117000},"page":"bcr2016217797","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Hypercalcaemia caused by active pulmonary tuberculosis in an elderly person without fever or pulmonary symptoms"],"prefix":"10.1136","volume":"2017","author":[{"given":"Shogo","family":"Hanai","sequence":"first","affiliation":[{"name":"Nakagami Byoin, Okinawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Shinzato","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Nakagami General Hospital, Okinawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daiki","family":"Inazu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Nakagami General Hospital, Okinawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuharu","family":"Tokuda","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine, Tsukuba University, Mito, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,2,24]]},"reference":[{"unstructured":"Ministry of Health, Welfare and Labour. Year 2014 tuberculosis registration survey database. http:\/\/www.mhlw.go.jp\/bunya\/kenkou\/kekkaku-kansenshou03\/14.html (accessed 5 Sep 2016).","key":"2025082707214156000_2017.feb24_1.bcr2016217797.1"},{"doi-asserted-by":"publisher","key":"2025082707214156000_2017.feb24_1.bcr2016217797.2","DOI":"10.1093\/qjmed\/77.3.1277"},{"key":"2025082707214156000_2017.feb24_1.bcr2016217797.3","first-page":"349","article-title":"Low incidence of hypercalcaemia in tuberculosis in Malaysia","volume":"96","author":"Tan","year":"1993","journal-title":"J Trop Med Hyg"},{"key":"2025082707214156000_2017.feb24_1.bcr2016217797.4","doi-asserted-by":"crossref","first-page":"23","DOI":"10.2169\/internalmedicine.46.6052","article-title":"The causes of hypercalcemia in Okinawan patients: an international comparison","volume":"46","author":"Tokuda","year":"2007","journal-title":"Intern Med"},{"key":"2025082707214156000_2017.feb24_1.bcr2016217797.5","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1164\/ajrccm\/138.4.984","article-title":"Vitamin D metabolism in tuberculosis. Production of 1,25(OH)2D3 by cells recovered by bronchoalveolar lavage and the role of this metabolite in calcium homeostasis","volume":"138","author":"Cadranel","year":"1988","journal-title":". Am Rev Respir Dis"},{"doi-asserted-by":"publisher","key":"2025082707214156000_2017.feb24_1.bcr2016217797.6","DOI":"10.1007\/s002239900192"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2016-217797","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:21:47Z","timestamp":1756304507000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2016-217797"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,24]]},"references-count":6,"alternative-id":["10.1136\/bcr-2016-217797"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2016-217797","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2017,2,24]]}}}