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The pathological findings demonstrated moderately differentiated SCC of the distal extrahepatic bile duct (T1N1M0, stage IIB). 6\u2005months after surgery, recurrence of the para-aortic lymph node was shown in abdominal CT. 5 courses of tegafur\/gimeracil\/oteracil (S-1) plus cisplatin therapy was performed and the para-aortic lymph node disappeared, confirmed as complete response by imaging findings. The patient is alive without recurrence, 10\u2005months after recurrence and chemotherapy.<\/jats:p>","DOI":"10.1136\/bcr-2016-218177","type":"journal-article","created":{"date-parts":[[2016,12,8]],"date-time":"2016-12-08T15:27:16Z","timestamp":1481210836000},"page":"bcr2016218177","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Squamous cell carcinoma of the extrahepatic bile duct with metachronous para-aortic lymph node metastasis successfully treated with S-1 plus cisplatin"],"prefix":"10.1136","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9216-4800","authenticated-orcid":false,"given":"Ryohei","family":"Nishiguchi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dal Ho","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayuki","family":"Honda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsuguo","family":"Sakamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2016,12,8]]},"reference":[{"key":"2025042705565722000_2016.dec08_1.bcr2016218177.1","first-page":"1260","article-title":"Case records of the Massachusetts General Hospital: case 16261","volume":"202","author":"Cabot","year":"1930","journal-title":"N Eng J Med"},{"key":"2025042705565722000_2016.dec08_1.bcr2016218177.2","unstructured":"Bosman FT , Carneiro F , Hruban RH , et al . 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