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Pathology specimens from theatre confirmed metastatic CCA. Despite sustaining a subsequent fractured neck of femur on the operative side, she recovered well from surgery, with minimal pain and improved mobility on discharge. She restarted palliative chemotherapy. This case illustrates the option of definitive major surgery for the management of metastatic bone disease. As in this case, this can lead to improved symptom control and quality of remaining life.<\/jats:p>","DOI":"10.1136\/bcr-2016-218616","type":"journal-article","created":{"date-parts":[[2017,3,27]],"date-time":"2017-03-27T13:13:49Z","timestamp":1490620429000},"page":"bcr2016218616","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Rare progression of cholangiocarcinoma: distal femoral metastasis"],"prefix":"10.1136","volume":"2017","author":[{"given":"Sam A","family":"MacKenzie","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joaquim Stanislas Olivier","family":"Goffin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Conor","family":"Rankin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom","family":"Carter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,3,27]]},"reference":[{"key":"2025042705444253000_2017.mar27_1.bcr2016218616.1","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2011.131"},{"key":"2025042705444253000_2017.mar27_1.bcr2016218616.2","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s12072-012-9407-y","article-title":"The risk factors and diagnosis of cholangiocarcinoma","volume":"7","author":"Wadsworth","year":"2013","journal-title":"Hepatol Int"},{"key":"2025042705444253000_2017.mar27_1.bcr2016218616.3","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1002\/jso.2930360107","article-title":"Primary liver cancer: pattern of metastasis","volume":"36","author":"Lee","year":"1987","journal-title":"J Surg Oncol"},{"key":"2025042705444253000_2017.mar27_1.bcr2016218616.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2008.09.008"},{"key":"2025042705444253000_2017.mar27_1.bcr2016218616.5","doi-asserted-by":"crossref","unstructured":"Carlisle RT , Roberts CS . 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