{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T20:33:14Z","timestamp":1791405194298,"version":"4.3.3"},"reference-count":10,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2017,2,3]]},"abstract":"<jats:p>Metal-induced encephalopathy after stent-assisted coil embolization is extremely rare. The present report describes two patients who presented with symptomatic intracranial parenchymal edematous lesions after stent-assisted coil embolization. A 64-year-old woman underwent stent-assisted coil embolization for a left internal carotid artery aneurysm; 21\u2005days after the procedure she presented with right hand weakness and MRI revealed multifocal white matter lesions. Another woman aged 52\u2005years underwent stent-assisted coil embolization for right vertebral artery aneurysm; 18\u2005days after the procedure she presented with left-sided sensory disturbance and MRI demonstrated multiple white matter lesions. Treatment in both cases resulted in improvement of these lesions after steroid pulse therapy, and the patients had no associated morbidity 4\u2005months after the procedures. Clinicians should monitor for neurologic symptoms and postoperative delayed radiologic parenchymal edematous changes associated with the metal allergic reaction after nitinol stent-assisted coil embolization.<\/jats:p>","DOI":"10.1136\/bcr-2017-013005","type":"journal-article","created":{"date-parts":[[2017,2,20]],"date-time":"2017-02-20T10:00:18Z","timestamp":1487584818000},"page":"bcr2017013005","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":12,"title":["Nickel-associated delayed multiple white matter lesions after stent-assisted coil embolization of intracranial unruptured aneurysm"],"prefix":"10.1136","volume":"2017","author":[{"given":"Hun Soo","family":"Park","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Nara Medical University, Kashihara, Nara, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ichiro","family":"Nakagawa","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Nara Medical University, Kashihara, Nara, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shohei","family":"Yokoyama","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Nara Medical University, Kashihara, Nara, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Wajima","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Nara Medical University, Kashihara, Nara, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Wada","sequence":"additional","affiliation":[{"name":"Department of Radiology, Nara Medical University, Kashihara, Nara, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Motoyama","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Nara Medical University, Kashihara, Nara, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimihiko","family":"Kichikawa","sequence":"additional","affiliation":[{"name":"Department of Radiology, Nara Medical University, Kashihara, Nara, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Nakase","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Nara Medical University, Kashihara, Nara, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2017,2,20]]},"reference":[{"key":"2025082804210810000_2017.feb20_1.bcr2017013005.1","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.1016\/j.jstrokecerebrovasdis.2016.05.035","article-title":"Safety and efficacy of Wingspan stenting for severe symptomatic atherosclerotic stenosis of the middle cerebral artery: analysis of 278 continuous cases","volume":"25","author":"Zhao","year":"2016","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"2025082804210810000_2017.feb20_1.bcr2017013005.2","first-page":"176","article-title":"North American Contact Dermatitis Group patch-test results, 2001\u20132002 study period","volume":"15","author":"Pratt","year":"2004","journal-title":"Dermatitis"},{"key":"2025082804210810000_2017.feb20_1.bcr2017013005.3","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0b013e3182819c51"},{"key":"2025082804210810000_2017.feb20_1.bcr2017013005.4","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2003.7"},{"key":"2025082804210810000_2017.feb20_1.bcr2017013005.5","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4636(19990605)45:3<251::AID-JBM13>3.0.CO;2-5"},{"key":"2025082804210810000_2017.feb20_1.bcr2017013005.6","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(97)00210-X"},{"key":"2025082804210810000_2017.feb20_1.bcr2017013005.7","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1007\/s00234-012-1048-2","article-title":"Reversible intracranial parenchymal changes in MRI after MCA aneurysm treatment with stent-assisted coiling technique; possible nickel allergy","volume":"54","author":"Ulus","year":"2012","journal-title":"Neuroradiology"},{"key":"2025082804210810000_2017.feb20_1.bcr2017013005.8","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1097\/00006123-199811000-00110","article-title":"Cell-mediated allergy to a cerebral aneurysm clip: case report","volume":"43","author":"Ross","year":"1998","journal-title":"Neurosurgery"},{"key":"2025082804210810000_2017.feb20_1.bcr2017013005.9","doi-asserted-by":"crossref","first-page":"924","DOI":"10.3171\/2014.6.JNS132405","article-title":"Cell-mediated allergy to cerebral aneurysm clip causing extensive cerebral edema","volume":"121","author":"Tan","year":"2014","journal-title":"J Neurosurg"},{"key":"2025082804210810000_2017.feb20_1.bcr2017013005.10","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/j.1600-0536.2011.01971.x","article-title":"Hypersensitivity reactions to metallic implants\u2014diagnostic algorithm and suggested patch test series for clinical use","volume":"66","author":"Schalock","year":"2012","journal-title":"Contact Derm"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2017-013005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:21:15Z","timestamp":1756380075000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2017-013005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,20]]},"references-count":10,"alternative-id":["10.1136\/bcr-2017-013005"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2017-013005","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,20]]}}}