{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T11:33:15Z","timestamp":1791891195409,"version":"4.3.4"},"reference-count":18,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2017,4,16]]},"abstract":"<jats:p>Ewing\u2019s sarcoma is a highly aggressive malignant tumour most commonly affecting long bones in children and adolescents. It is part of the Ewing\u2019s sarcoma family of tumours (ESFTs) that also include peripheral primitive neuroectodermal tumour and Askin\u2019s tumours. ESFTs share common cytogenetic aberrations, antigenic profiles and proto-oncogene expression with an overall similar clinical course. In 99% of ESFTs, genetic translocation with molecular fusion involves the EWSR1 gene on 22q12. Approximately 30% of ESFTs are extraosseous, most commonly occurring in the soft tissues of extremities, pelvis, retroperitoneum and chest wall. Primary presentation in solid organs is very rare but has been described in multiple sites including the pancreas. Accurate diagnosis of a Ewing\u2019s sarcoma in a solid organ is critical in facilitating correct treatment. We report the case of a 17-year-old girl with cytogenetically confirmed primary pancreatic Ewing\u2019s sarcoma and provide a brief review of the published literature.<\/jats:p>","DOI":"10.1136\/bcr-2017-219219","type":"journal-article","created":{"date-parts":[[2017,5,4]],"date-time":"2017-05-04T13:45:20Z","timestamp":1493905520000},"page":"bcr-2017-219219","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":12,"title":["Cytogenetically confirmed primary Ewing\u2019s sarcoma of the 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