{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T23:22:08Z","timestamp":1772234528528,"version":"3.50.1"},"reference-count":19,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2017,3,15]]},"abstract":"<jats:p>Endarteritis is a major complication in patients with patent ductus arteriosus, causing significant morbidity and mortality. We report an adult patient with asymptomatic patent ductus arteriosus and endarteritis involving the main pulmonary artery and secondary infective spondylodiscitis at the L5\u2013S1 intervertebral disc caused by <jats:italic>Abiotrophia defectiva<\/jats:italic>. <jats:italic>A. defectiva<\/jats:italic>, commonly referred to as nutritionally variant streptococci, cannot be identified easily by conventional blood culture techniques from clinical specimens. Its isolation was confirmed by 16S ribosomal RNA sequencing. The patient was successfully managed with a combination of penicillin G and gentamicin, pending surgical repair of the patent ductus arteriosus.<\/jats:p>","DOI":"10.1136\/bcr-2017-219295","type":"journal-article","created":{"date-parts":[[2017,4,7]],"date-time":"2017-04-07T07:55:18Z","timestamp":1491551718000},"page":"bcr-2017-219295","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["<i>Abiotrophia defectiva<\/i> endarteritis with infective spondylodiscitis in an adult patient with patent ductus arteriosus"],"prefix":"10.1136","volume":"2017","author":[{"given":"Angel T","family":"Miraclin","sequence":"first","affiliation":[{"name":"Department of General Medicine, Christian Medical College and Hospital, Vellore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susmitha K","family":"Perumalla","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology, Christian Medical College and Hospital, Vellore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaifrin","family":"Daniel","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Christian Medical College and Hospital, Vellore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sowmya","family":"Sathyendra","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Christian Medical College and Hospital, Vellore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,4,7]]},"reference":[{"key":"2025082801415621000_2017.apr07_1.bcr-2017-219295.1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/BF03086157","article-title":"Patent ductus arteriosus in adults: case report and review illustrating the spectrum of the disease","volume":"16","author":"Wiyono","year":"2008","journal-title":"Neth Heart J"},{"key":"2025082801415621000_2017.apr07_1.bcr-2017-219295.2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.30.1.4"},{"key":"2025082801415621000_2017.apr07_1.bcr-2017-219295.3","first-page":"1242","article-title":"[Abiotrophia defectiva: an unusual cause of endocarditis]","volume":"12","author":"Baroz","year":"2016","journal-title":"Rev Med Suisse"},{"key":"2025082801415621000_2017.apr07_1.bcr-2017-219295.4","doi-asserted-by":"crossref","unstructured":"Pinkney JA , Nagassar RP , Roye-Green KJ , et al . Abiotrophia defectiva endocarditis. BMJ Case Rep 2014.doi:10.1136\/bcr-2014-207361","DOI":"10.1136\/bcr-2014-207361"},{"key":"2025082801415621000_2017.apr07_1.bcr-2017-219295.5","first-page":"111","article-title":"Destructive Abiotrophia defectiva endocarditis","volume":"20","author":"Kalavakunta","year":"2011","journal-title":"J Heart Valve Dis"},{"key":"2025082801415621000_2017.apr07_1.bcr-2017-219295.6","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00074-09"},{"key":"2025082801415621000_2017.apr07_1.bcr-2017-219295.7","first-page":"313","article-title":"Patent ductus arteriosus with infective pulmonary endarteritis","volume":"32","author":"Manges","year":"1916","journal-title":"Trans Am Climatol Clin Assoc"},{"key":"2025082801415621000_2017.apr07_1.bcr-2017-219295.8","doi-asserted-by":"publisher","DOI":"10.1007\/s11748-010-0729-1"},{"key":"2025082801415621000_2017.apr07_1.bcr-2017-219295.9","doi-asserted-by":"crossref","first-page":"e16","DOI":"10.4081\/hi.2011.e16","article-title":"Large patent ductus arteriosus in an adult complicated by pulmonary endarteritis and embolic lung abscess","volume":"6","author":"Navaratnarajah","year":"2011","journal-title":"Heart Int"},{"key":"2025082801415621000_2017.apr07_1.bcr-2017-219295.10","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1111\/j.0742-2822.2004.04013.x","article-title":"Patent ductus arteriosus complicated by pulmonary artery endarteritis in an adult","volume":"21","author":"Kadakia","year":"2004","journal-title":"Echocardiography"},{"key":"2025082801415621000_2017.apr07_1.bcr-2017-219295.11","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.2169\/internalmedicine.52.0897","article-title":"Patent ductus arteriosus with pulmonary endarteritis","volume":"52","author":"Sugimura","year":"2013","journal-title":"Intern Med"},{"key":"2025082801415621000_2017.apr07_1.bcr-2017-219295.12","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1177\/000331970405500115","article-title":"Pulmonary endarteritis and subsequent embolization to the lung as a complication of a patent ductus arteriosus\u2014a case report","volume":"55","author":"Bilge","year":"2004","journal-title":"Angiology"},{"key":"2025082801415621000_2017.apr07_1.bcr-2017-219295.13","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-7-1-77"},{"key":"2025082801415621000_2017.apr07_1.bcr-2017-219295.14","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.39.10.3520-3523.2001"},{"key":"2025082801415621000_2017.apr07_1.bcr-2017-219295.15","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-45-4-798"},{"key":"2025082801415621000_2017.apr07_1.bcr-2017-219295.16","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02654-12"},{"key":"2025082801415621000_2017.apr07_1.bcr-2017-219295.17","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0255-0857(21)03195-9","article-title":"Satelliting streptococci in an adult male with foetal heart","volume":"20","author":"Jayakeerthi","year":"2002","journal-title":"Indian J Med Microbiol"},{"key":"2025082801415621000_2017.apr07_1.bcr-2017-219295.18","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-6-9"},{"key":"2025082801415621000_2017.apr07_1.bcr-2017-219295.19","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.165564"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2017-219295","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T08:42:05Z","timestamp":1756370525000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2017-219295"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,7]]},"references-count":19,"alternative-id":["10.1136\/bcr-2017-219295"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2017-219295","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,7]]}}}