{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:04:51Z","timestamp":1756425891308,"version":"3.44.0"},"reference-count":15,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2017,4,19]]},"abstract":"<jats:p>An 88-year-old man with history of bioprosthetic aortic valve replacement was hospitalised with fever, chills, malaise and right lower extremity cellulitis. Laboratory investigations revealed leucocytosis and blood cultures grew <jats:italic>Helcococcus kunzii<\/jats:italic>. Although transoesophageal echocardiography was negative for endocarditis, the patient was treated with 4\u2009week of intravenous ceftriaxone. However, he was readmitted 6\u2009weeks later with symptoms of fever, chills and hypoxia in setting of recurrent <jats:italic>H. kunzii<\/jats:italic> bacteraemia. A repeat transoesophageal echocardiogram revealed a mobile mass on bioprosthetic aortic valve, severe perivalvular insufficiency with pseudoaneurysm formation, and severe native mitral and tricuspid valve regurgitation. Cardiothoracic surgery was consulted and the patient underwent replacement of aortic valve and aortic root, and tricuspid and mitral valve repairs. Histological examination of excised bioprosthetic aortic valve revealed active endocarditis with cocci identified on silver stain. Patient was successfully treated with 4-week course of intravenous ceftriaxone and was doing well at 2-year follow-up.<\/jats:p>","DOI":"10.1136\/bcr-2017-219330","type":"journal-article","created":{"date-parts":[[2017,5,4]],"date-time":"2017-05-04T02:05:10Z","timestamp":1493863510000},"page":"bcr-2017-219330","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["<i>Helcococcus kunzii<\/i> prosthetic valve endocarditis secondary to lower extremity cellulitis"],"prefix":"10.1136","volume":"2017","author":[{"given":"Saira","family":"Farid","sequence":"first","affiliation":[{"name":"Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Miranda","sequence":"additional","affiliation":[{"name":"Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Maleszewski","sequence":"additional","affiliation":[{"name":"Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Rizwan","family":"Sohail","sequence":"additional","affiliation":[{"name":"Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,5,3]]},"reference":[{"key":"2025082805245253000_2017.may03_1.bcr-2017-219330.1","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-43-3-425"},{"key":"2025082805245253000_2017.may03_1.bcr-2017-219330.2","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-49-4-1429"},{"key":"2025082805245253000_2017.may03_1.bcr-2017-219330.3","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.63077-0"},{"key":"2025082805245253000_2017.may03_1.bcr-2017-219330.4","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.03076-13"},{"key":"2025082805245253000_2017.may03_1.bcr-2017-219330.5","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.6.2872-2874.2004"},{"key":"2025082805245253000_2017.may03_1.bcr-2017-219330.6","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00947-15"},{"key":"2025082805245253000_2017.may03_1.bcr-2017-219330.7","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1128\/jcm.33.6.1638-1638.1995","article-title":"Helcococcus, a new genus of catalase-negative, gram-positive cocci isolated from clinical specimens","volume":"33","author":"Caliendo","year":"1995","journal-title":"J Clin Microbiol"},{"key":"2025082805245253000_2017.may03_1.bcr-2017-219330.8","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.2008\/000471-0"},{"key":"2025082805245253000_2017.may03_1.bcr-2017-219330.9","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1128\/jcm.35.1.328-329.1997","article-title":"Helcococcus kunzii as sole isolate from an infected sebaceous cyst","volume":"35","author":"Peel","year":"1997","journal-title":"J Clin Microbiol"},{"key":"2025082805245253000_2017.may03_1.bcr-2017-219330.10","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1186\/s12879-015-0984-y","article-title":"Infectious endocarditis caused by Helcococcus kunzii in a vascular patient: a case report and literature review","volume":"15","author":"Lotte","year":"2015","journal-title":"BMC Infect Dis"},{"key":"2025082805245253000_2017.may03_1.bcr-2017-219330.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2011.04.010"},{"key":"2025082805245253000_2017.may03_1.bcr-2017-219330.12","doi-asserted-by":"crossref","first-page":"2377","DOI":"10.1128\/JCM.36.8.2377-2379.1998","article-title":"Breast abscess associated with Helcococcus kunzii","volume":"36","author":"Chagla","year":"1998","journal-title":"J Clin Microbiol"},{"key":"2025082805245253000_2017.may03_1.bcr-2017-219330.13","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02550-13"},{"key":"2025082805245253000_2017.may03_1.bcr-2017-219330.14","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2012.01.007"},{"key":"2025082805245253000_2017.may03_1.bcr-2017-219330.15","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.12.6205-6208.2005"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2017-219330","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:25:01Z","timestamp":1756383901000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2017-219330"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,3]]},"references-count":15,"alternative-id":["10.1136\/bcr-2017-219330"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2017-219330","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2017,5,3]]}}}