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She then presented with a vaginal relapse and an isolated hepatic lesion, both of which were proposed for surgery. The diagnosis of MM of the cervix is a clinical and pathological challenge due to its rarity and overlapping features. Cytology cannot accurately diagnose it. Moreover, amelanotic MMs must be distinguished from other poorly differentiated carcinomas by diagnosis that ultimately relies on immunohistochemical staining. Radical surgery is the only treatment showing predictive benefit.<\/jats:p>","DOI":"10.1136\/bcr-2017-219361","type":"journal-article","created":{"date-parts":[[2017,4,21]],"date-time":"2017-04-21T08:24:05Z","timestamp":1492763045000},"page":"bcr-2017-219361","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Primary malignant melanoma of the cervix: a rare disease"],"prefix":"10.1136","volume":"2017","author":[{"given":"Ivo","family":"Juli\u00e3o","sequence":"first","affiliation":[{"name":"Medical Oncology, Instituto Portugu\u00eas de Oncologia do Porto Francisco Gentil, Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonia Dias","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Department of Pathology, Instituto Portugu\u00eas de Oncologia do Porto Francisco Gentil, Porto, 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