{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:23:58Z","timestamp":1761153838051,"version":"3.40.4"},"reference-count":16,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2017,6,9]]},"abstract":"<jats:p>Carney complex is a rare genetic disease characterised by a complex of myxomas, spotty pigmentation and endocrine overactivity. At diagnosis, about one-third of male patients presents with testicular tumours, namely large cell calcifying Sertoli cell tumours, which are often multicentric and\/or bilateral and have a low malignant potential. Although radical orchiectomy is the gold standard for the treatment of testicular neoplasms, a conservative approach with partial orchiectomy or tumourectomy may be the best treatment option for these patients, allowing the preservation of endocrine function, fertility and body image. We present a case of a 19-year-old man with a known history of Carney complex with early identification of a small testicular tumour treated with organ-sparing surgery.<\/jats:p>","DOI":"10.1136\/bcr-2017-219557","type":"journal-article","created":{"date-parts":[[2017,7,14]],"date-time":"2017-07-14T11:51:32Z","timestamp":1500033092000},"page":"bcr-2017-219557","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Organ-sparing surgery for large cell calcifying Sertoli cell tumour in a patient with Carney complex"],"prefix":"10.1136","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5075-0067","authenticated-orcid":false,"given":"Maria Jos\u00e9","family":"Freire","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Nunes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu\u00c3\u00ads","family":"Sousa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnaldo","family":"Figueiredo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,7,14]]},"reference":[{"key":"2025042712081202000_2017.jul14_2.bcr-2017-219557.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(12)61843-6"},{"key":"2025042712081202000_2017.jul14_2.bcr-2017-219557.2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.86.9.4041"},{"key":"2025042712081202000_2017.jul14_2.bcr-2017-219557.3","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19981102)80:2<183::AID-AJMG19>3.0.CO;2-I"},{"key":"2025042712081202000_2017.jul14_2.bcr-2017-219557.4","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/S0022-5347(05)65285-8","article-title":"Testicular tumors in Carney's complex","volume":"167","author":"Washecka","year":"2002","journal-title":"J Urol"},{"key":"2025042712081202000_2017.jul14_2.bcr-2017-219557.5","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/74.5.607"},{"key":"2025042712081202000_2017.jul14_2.bcr-2017-219557.6","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-198507000-00007"},{"key":"2025042712081202000_2017.jul14_2.bcr-2017-219557.7","doi-asserted-by":"publisher","DOI":"10.1038\/79238"},{"key":"2025042712081202000_2017.jul14_2.bcr-2017-219557.8","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/9.20.3037"},{"key":"2025042712081202000_2017.jul14_2.bcr-2017-219557.9","doi-asserted-by":"publisher","DOI":"10.1159\/000345669"},{"key":"2025042712081202000_2017.jul14_2.bcr-2017-219557.10","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2008-2333"},{"key":"2025042712081202000_2017.jul14_2.bcr-2017-219557.11","doi-asserted-by":"publisher","DOI":"10.1097\/CCO.0b013e32801195eb"},{"key":"2025042712081202000_2017.jul14_2.bcr-2017-219557.12","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1016\/j.juro.2007.03.071","article-title":"Large cell calcifying Sertoli cell tumor of testis","volume":"177","author":"Halat","year":"2007","journal-title":"J Urol"},{"key":"2025042712081202000_2017.jul14_2.bcr-2017-219557.13","doi-asserted-by":"publisher","DOI":"10.1210\/me.2006-0060"},{"key":"2025042712081202000_2017.jul14_2.bcr-2017-219557.14","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2010.01.014"},{"key":"2025042712081202000_2017.jul14_2.bcr-2017-219557.15","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(03)00465-5"},{"key":"2025042712081202000_2017.jul14_2.bcr-2017-219557.16","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-011-0100-1"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2017-219557","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T19:08:20Z","timestamp":1745780900000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2017-219557"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,14]]},"references-count":16,"alternative-id":["10.1136\/bcr-2017-219557"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2017-219557","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2017,7,14]]}}}